SCHEMBL18179775

SCHEMBL18179775

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C2c1ccccc1CO

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
NPC1 O15118 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
USP2 O75604 3/20 0.43
GAA P10253 3/20 0.43
CYP3A4 P08684 2/20 0.43
HTT P42858 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
CYP2C19 P33261 1/20 0.43
BRCA1 P38398 1/20 0.43
CASP7 P55210 1/20 0.43
HBB P68871 1/20 0.43
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18606132 0.94 ALDH1A1 (0.43) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL18213652 0.86 LMNA (0.49) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL18623952 0.86 ALDH1A1 (0.37) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL18623953 0.83 SMN1; SMN2 (0.35) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL4070707 0.82 NPC1 (0.45) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL3907415 0.81 MEN1 (0.44) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL12372186 0.81 MAPT (0.43) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL18623951 0.80 GAA (0.33) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL10082360 0.80 CYP2C9 (0.59) MEN1KMT2ANPC1NPSR1SMN1; SMN2
SCHEMBL30539519 0.80 CYP2C9 (0.59) MEN1KMT2ANPC1NPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10684294-B2 Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical THE UNIVERSITY OF HONG KONG (HK) 2020-06-16 US disclosed
US-9939568-B2 Photosensitive resin composition for color filter and application of the same CHI MEI CORPORATION (TW) 2018-04-10 US disclosed
US-9939568-B2 Photosensitive resin composition for color filter and application of the same CHI MEI CORPORATION (TW) 2018-04-10 US disclosed
US-20160327863-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION OF THE SAME CHI MEI CORPORATION (TW) 2016-11-10 US disclosed
US-20160327863-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR COLOR FILTER AND APPLICATION OF THE SAME CHI MEI CORPORATION (TW) 2016-11-10 US disclosed
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL VERSITECH LIMITED (HK) 2016-10-27 US disclosed
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL VERSITECH LIMITED (HK) 2016-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160312033-A1 DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL HAGH, HADH, FECH MEN1 2287/4885KMT2A 1828/4885NPC1 2588/4885
US-10684294-B2 Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical HAGH, HADH, FECH MEN1 2287/4885KMT2A 1828/4885NPC1 2588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.