Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907344 | 0.79 | ADRA2C (0.46) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL3916722 | 0.75 | QPCT (0.53) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL3902108 | 0.74 | ADORA2A (0.40) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL27466376 | 0.70 | CD44 (0.46) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL1132878 | 0.69 | CYP2A6 (0.45) | MEN1USP2KMT2AGAAMAPT | |
| SCHEMBL1122539 | 0.69 | MAPT (0.53) | MEN1USP2CASP1BRCA1CASP7 | |
| SCHEMBL442009 | 0.68 | MAPT (0.70) | MEN1KMT2AGAAMAPTHTT | |
| SCHEMBL29512293 | 0.68 | MAPT (0.70) | MEN1KMT2AGAAMAPTHTT | |
| SCHEMBL29512292 | 0.68 | MAPT (0.70) | MEN1KMT2AGAAMAPTHTT | |
| SCHEMBL3915600 | 0.68 | MEN1 (0.45) | MEN1USP2CASP1BRCA1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |