Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133289 | 0.78 | MGAM (0.47) | MEN1KMT2ALTA4HGAAALDH1A1 | |
| SCHEMBL3907480 | 0.74 | MEN1 (0.42) | MEN1KMT2AUSP2CASP1CASP7 | |
| SCHEMBL3907344 | 0.72 | ADRA2C (0.46) | MEN1KMT2AUSP2CASP1CASP7 | |
| SCHEMBL6371894 | 0.72 | CD44 (0.45) | MEN1KMT2ALTA4HGAAALDH1A1 | |
| SCHEMBL11869781 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2ALTA4HGAAALDH1A1 | |
| SCHEMBL27912112 | 0.70 | KDM4E (0.46) | ADORA2AADORA1MEN1KMT2ACASP1 | |
| SCHEMBL28222648 | 0.70 | LTA4H (0.57) | MEN1KMT2ALTA4HGAAALDH1A1 | |
| SCHEMBL27466376 | 0.70 | CD44 (0.46) | MEN1KMT2AUSP2CASP1CASP7 | |
| SCHEMBL1122539 | 0.69 | MAPT (0.53) | MEN1KMT2AUSP2CASP1CASP7 | |
| SCHEMBL3916722 | 0.69 | QPCT (0.53) | MEN1KMT2AUSP2CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |