Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907344 | 0.80 | ADRA2C (0.46) | QPCTMEN1KMT2AUSP2CASP1 | |
| SCHEMBL3907783 | 0.78 | MEN1 (0.39) | QPCTMEN1KMT2AUSP2CASP1 | |
| SCHEMBL30507348 | 0.78 | MGAM (0.46) | QPCTMAPTHTTTSHRMGAM | |
| SCHEMBL3907480 | 0.75 | MEN1 (0.42) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL3915600 | 0.75 | MEN1 (0.45) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL3904575 | 0.74 | MEN1 (0.44) | QPCTMEN1KMT2AUSP2CASP1 | |
| SCHEMBL3904434 | 0.74 | QPCT (0.49) | QPCTMEN1KMT2AUSP2CASP1 | |
| SCHEMBL1015853 | 0.72 | CYP3A4 (0.53) | MEN1KMT2AMAPTHTTTSHR | |
| SCHEMBL9681067 | 0.71 | CD44 (0.46) | QPCTMAPTHTTTSHRMGAM | |
| SCHEMBL27466376 | 0.71 | CD44 (0.46) | MEN1KMT2AUSP2CASP1BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |