Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908170 | 1.00 | REN (0.38) | RENCYP3A4TSHRMAPTTP53 | |
| SCHEMBL3908957 | 0.91 | REN (0.31) | REN | |
| SCHEMBL3908955 | 0.91 | REN (0.31) | REN | |
| SCHEMBL3902381 | 0.87 | REN (0.31) | REN | |
| SCHEMBL3902386 | 0.87 | REN (0.31) | REN | |
| SCHEMBL3908167 | 0.81 | REN (0.37) | RENCYP3A4TSHRMAPTTP53 | |
| SCHEMBL3915729 | 0.78 | TSHR (0.38) | RENCYP3A4TSHRMAPTTP53 | |
| SCHEMBL2683235 | 0.75 | REN (0.39) | RENCYP3A4TSHRMAPTTP53 | |
| SCHEMBL3908950 | 0.73 | RORC (0.32) | RENPOLB | |
| SCHEMBL2924106 | 0.71 | MAPT (0.37) | RENCYP3A4TSHRMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |