Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908950 | 0.90 | RORC (0.32) | RENPOLBKMT2A | |
| SCHEMBL3902379 | 0.86 | RORC (0.32) | REN | |
| SCHEMBL3908170 | 0.81 | REN (0.38) | RENMAPTCYP3A4TP53POLB | |
| SCHEMBL3908172 | 0.81 | REN (0.38) | RENMAPTCYP3A4TP53POLB | |
| SCHEMBL3916695 | 0.80 | KMT2A (0.34) | RENMAPTPOLBTHRBKMT2A | |
| SCHEMBL3916692 | 0.80 | KMT2A (0.34) | RENMAPTPOLBTHRBKMT2A | |
| SCHEMBL3915726 | 0.79 | POLB (0.40) | RENMAPTTP53POLBTHRB | |
| SCHEMBL3908343 | 0.78 | MAPT (0.42) | RENMAPTCYP3A4TP53POLB | |
| SCHEMBL2683234 | 0.77 | REN (0.40) | RENMAPTTP53POLBTHRB | |
| SCHEMBL3903708 | 0.76 | GAA (0.35) | MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |