Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471354 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL18055562 | 0.83 | KDM4E (0.43) | ALDH1A1AURKAKDM4EMEN1KMT2A | |
| SCHEMBL11703204 | 0.81 | MEN1 (0.41) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL29986241 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL10102084 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL23758044 | 0.80 | L3MBTL1 (0.51) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL25569641 | 0.79 | MAPK1 (0.44) | ALDH1A1AURKAKDM4EMEN1KMT2A | |
| SCHEMBL11326931 | 0.75 | MAPK8 (0.51) | ALDH1A1AURKAKDM4EKMT2AHSD17B10 | |
| SCHEMBL11739178 | 0.74 | MAPK8 (0.51) | ALDH1A1AURKAKDM4EHSD17B10HPGD | |
| SCHEMBL11720169 | 0.74 | CCNA2 (0.44) | ALDH1A1AURKAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2015848-A1 | 2, 3, 4, 6-SUBSTITUTED PYRIDINES AND THEIR USE AS HAIR DYEING COMPOSITIONS | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007122197-A1 | 2, 3, 4, 6-SUBSTITUTED PYRIDINES AND THEIR USE AS HAIR DYEING COMPOSITIONS | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-11-01 | — | — | WO | disclosed |
| EP-1849500-A1 | 2, 3, 4, 6-Substituted pyridines and their use as hair dyeing compositions | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-4134887-A | FIBER-REACTIVE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |
| US-4066638-A | WATER-SOLUBLE FIBER REACTIVE PHENYL-AZO-NAPHTHYL DYESTUFFS CONTAINING TWO SULFO GROUPS IN THE PHENYL MOIETY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
| US-4061642-A | AZO DYE INTERMEDIATES | CASSELLA FARBWERKE MAINKUR AG (DT) | 1977-12-06 | — | — | US | disclosed |
| US-3980659-A | INSECTICIDES, INTERMEDIATES FOR AZO DYES | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3956294-A | AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3954782-A | 2,6-Hydrazino-3-pyridine carboxyamides | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-04 | — | — | US | disclosed |
| US-3947463-A | Certain 2-amino-nicotinonitrile derivatives | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-30 | — | — | US | disclosed |
| US-3946024-A | INTERMEDIATES FOR AZO DYES | CASSELLA FARBWERKE MAINKUR AG (DT) | 1976-03-23 | — | — | US | disclosed |