Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3918912 | 0.89 | CHRNB2 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL4058279 | 0.88 | CHRNA3 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL3919733 | 0.85 | HRH3 (0.39) | — | |
| SCHEMBL3919752 | 0.85 | CHRNA3 (0.36) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL3910190 | 0.83 | HRH3 (0.40) | CHRNB4CHRNA3CHRNB2CHRNA5 | |
| SCHEMBL3912530 | 0.80 | HRH3 (0.36) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL3919541 | 0.80 | HRH3 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA5 | |
| SCHEMBL3909210 | 0.80 | CHRNA3 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL3919056 | 0.79 | HRH3 (0.37) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL3910096 | 0.76 | HRH3 (0.35) | CHRNB4CHRNA3CHRNB2CHRNA5CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840158-B1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2009-02-18 | — | — | EP | disclosed |