Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895801 | 0.81 | SLC6A2 (0.32) | SLC6A3 | |
| SCHEMBL3899768 | 0.80 | ACHE (0.43) | MAPTHPGDSLC6A3ALDH1A1GAA | |
| SCHEMBL4098337 | 0.78 | SLC6A3 (0.42) | MAPTHPGDSLC6A3MEN1KMT2A | |
| SCHEMBL3908584 | 0.76 | NPC1 (0.49) | NPC1RAB9AMAPTATMHPGD | |
| SCHEMBL3909908 | 0.72 | ACHE (0.44) | NPC1RAB9AMAPTHPGDMAPK1 | |
| SCHEMBL3900452 | 0.71 | ACHE (0.45) | MAPTHPGDMAPK1MEN1KMT2A | |
| SCHEMBL3902804 | 0.69 | ALDH1A1 (0.36) | NPC1RAB9AMAPTHPGDMAPK1 | |
| SCHEMBL3908430 | 0.68 | ACHE (0.33) | MAPTMAPK1HSD17B10 | |
| SCHEMBL3899791 | 0.68 | ACHE (0.39) | MAPTMAPK1ALDH1A1KDM4EGAA | |
| SCHEMBL3897271 | 0.67 | JAK3 (0.36) | HPGDUSP2ALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632106-B2 | Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MFG CO (JP) | 2009-02-25 | — | — | EP | disclosed |
| EP-0632106-B1 | Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MFG CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0654472-B1 | Process for the production of 6,13-dihydroquinacridones | TOYO INK MFG CO (JP) | 2000-03-29 | — | — | EP | disclosed |
| US-5817817-A | Process for the production of 2,5-di(arylamino)-3,6-dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5659036-A | Process for the production of 2,5-di(arylamino)-3,6-dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MANUFACTURING CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5610306-A | ALCOHOL ELIMINATION REACTION OF 2,5-DI(PHENYLAMINO)-3,6--DIHYDROTEREPHTHALIC ACID DIALKYL ESTER; CYCLIZATION | TOYO INK MANUFACTURING CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0654472-A1 | Process for the production of 6,13-dihydroquinacridones and apparatus for use for the production | TOYO INK MANUFACTURING CO., LTD. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0632106-A1 | Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate | TOYO INK MANUFACTURING CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |