Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914955 | 0.92 | CYP3A4 (0.45) | KMT2AABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL3910178 | 0.88 | KDM4E (0.43) | KMT2AABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL14919008 | 0.82 | TSHR (0.55) | KMT2AABCB11CYP3A4ADRA2BOPRD1 | |
| SCHEMBL3914292 | 0.82 | CYP19A1 (0.52) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3918051 | 0.81 | L3MBTL1 (0.45) | KMT2ACYP3A4MAPTKDM4ELMNA | |
| SCHEMBL17641405 | 0.79 | KDM4E (0.57) | KMT2AMAPTKDM4ELMNAL3MBTL1 | |
| SCHEMBL3912012 | 0.78 | APP (0.47) | KMT2AMAPTKDM4EL3MBTL1TSHR | |
| SCHEMBL9928660 | 0.76 | CYP3A4 (0.66) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL3916941 | 0.74 | CYP19A1 (0.50) | LMNAL3MBTL1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4350526 | 0.74 | KMT2A (0.47) | KMT2AMAPTKDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090277559-A1 | METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1840158-B1 | METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2009-02-18 | — | — | EP | disclosed |