Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 3/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919967 | 0.84 | KDM4E (0.52) | CYP2A6KDM4EALDH1A1SMN1; SMN2NUDT1 | |
| SCHEMBL3909975 | 0.84 | KDM4E (0.57) | CYP2A6KDM4EALDH1A1SMN1; SMN2NUDT1 | |
| SCHEMBL3911184 | 0.81 | KDM4E (0.49) | CYP2A6KDM4EALDH1A1SMN1; SMN2NUDT1 | |
| SCHEMBL3913834 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2NUDT1FYN | |
| SCHEMBL3917455 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2NUDT1FYN | |
| SCHEMBL3910497 | 0.80 | KDM4E (0.46) | CYP2A6KDM4EALDH1A1SMN1; SMN2NUDT1 | |
| SCHEMBL3910189 | 0.79 | JAK2 (0.43) | CYP2A6 | |
| SCHEMBL3911140 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2NUDT1NPC1 | |
| SCHEMBL3910529 | 0.78 | ALDH1A1 (0.45) | CYP2A6KDM4EALDH1A1SMN1; SMN2NUDT1 | |
| SCHEMBL3923734 | 0.78 | DYRK1A (0.48) | KDM4EALDH1A1SMN1; SMN2NUDT1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524860-B2 | Antibacterial agents | PFIZER INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080021059-A1 | Antibacterial Agents | PFIZER INC. (US) | 2008-01-24 | — | — | US | disclosed |
| EP-1799680-A2 | TRIAZOLOPYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038116-A2 | TRIAZOLOPYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021059-A1 | Antibacterial Agents | CLPP, QDPR, CLSPN | CYP2A6 1897/4885KDM4E 3745/4885ALDH1A1 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.