SCHEMBL3909266

SCHEMBL3909266

COC(C)OC(C)O[Si](CCCOC(=O)Cc1ccccn1)(OC(C)OC(C)OC)OC(C)OC(C)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 3/20 0.37
ALDH1A1 P00352 2/20 0.37
PGR P06401 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
HDAC6 Q9UBN7 4/20 0.35
HDAC1 Q13547 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
NAAA Q02083 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3910730 0.93 CYP1A2 (0.38) HPGDHSD17B10CYP1A2ALDH1A1PGR
SCHEMBL3912380 0.86 CYP1A2 (0.40) CYP1A2ALDH1A1PGRADORA3PTGS1
SCHEMBL3909219 0.83 HPGD (0.43) HPGDHSD17B10CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL3911548 0.82 APP (0.50) ALDH1A1SMN1; SMN2MEN1KMT2APOLB
SCHEMBL3916939 0.81 CYP19A1 (0.55) ALDH1A1TSHR
SCHEMBL3913811 0.79 HPGD (0.44) HPGDHSD17B10CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL3919103 0.77 HSD17B10 (0.43) HPGDHSD17B10CYP1A2ALDH1A1HDAC6
SCHEMBL3909271 0.76 HPGD (0.41) HPGDHSD17B10CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL3916987 0.76 KMT2A (0.45) HPGDHSD17B10CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL356002 0.75 HSD17B10 (0.56) HPGDHSD17B10CYP1A2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed