SCHEMBL3911548

SCHEMBL3911548

COC(C)OC(C)O[Si](CCCOC(=O)c1ccccn1)(OC(C)OC(C)OC)OC(C)OC(C)OC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
PKM P14618 1/20 0.44
ALDH1A1 P00352 7/20 0.42
L3MBTL1 Q9Y468 5/20 0.39
KDM4E B2RXH2 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTT P42858 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912008 0.93 APP (0.46) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL4349768 0.85 PKM (0.47) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL4347761 0.82 APP (0.59) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3909266 0.82 HPGD (0.38) ALDH1A1SMN1; SMN2POLBMAPTKMT2A
SCHEMBL3914954 0.80 ALDH1A1 (0.40) ALDH1A1L3MBTL1KDM4ESMN1; SMN2MAPT
SCHEMBL3911717 0.78 APP (0.56) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3919094 0.76 APP (0.57) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3911551 0.75 APP (0.51) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3910730 0.74 CYP1A2 (0.38) ALDH1A1KDM4ESMN1; SMN2NPSR1POLB
SCHEMBL3911394 0.74 APP (0.54) APPPKMALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed