Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5640336 | 0.82 | BCHE (0.54) | L3MBTL1MEN1KMT2AMAPTMGLL | |
| SCHEMBL11511690 | 0.81 | MEN1 (0.60) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL11653014 | 0.80 | L3MBTL1 (0.86) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL11160314 | 0.80 | MAPT (0.63) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL3907319 | 0.79 | L3MBTL1 (0.70) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL13664721 | 0.79 | MAOA (0.51) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL3415388 | 0.79 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AMAPTPLAAT3 | |
| SCHEMBL613010 | 0.76 | ALDH1A1 (0.60) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL24375975 | 0.76 | L3MBTL1 (0.95) | L3MBTL1MEN1KMT2AMAPTATM | |
| SCHEMBL21186859 | 0.76 | L3MBTL1 (0.95) | L3MBTL1MEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |