Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397901 | 0.94 | MAPK1 (0.46) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL12882875 | 0.94 | MAPK1 (0.46) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL28319664 | 0.94 | MAPK1 (0.46) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL20745410 | 0.94 | MAPK1 (0.46) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL3449015 | 0.89 | PARL (0.50) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL30011527 | 0.83 | ALDH1A1 (0.50) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL85631 | 0.82 | ALDH1A1 (0.50) | CA2HPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL3133897 | 0.82 | PSIP1 (0.45) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL778545 | 0.82 | PSIP1 (0.50) | MAPK1PSIP1CA2PARLKMT2A | |
| SCHEMBL5945104 | 0.81 | PARL (0.47) | MAPK1PSIP1CA2PARLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8311324-A | — | — | None | — | — | JP | disclosed |
| US-8921515-B2 | Methods and compositions of preparation for proteome analysis | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| CN-103880697-A | N-dimethoxyethyl-m-aminoacetanilide synthesis process | JIANGSU DAOBO CHEMICAL CO LTD | 2014-06-25 | — | — | CN | disclosed |
| US-20130172539-A1 | METHODS AND COMPOSITIONS OF PREPARATION FOR PROTEOME ANALYSIS | CASE WESTERN RESERVE UNIVERSITY (US) | 2013-07-04 | — | — | US | disclosed |
| EP-1686188-B1 | Thin membrane for measuring protease activity | FUJIFILM CORP (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-1270736-B1 | FILMS FOR ASSAYING PROTEASE ACTIVITY | FUJIFILM CORP (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-1686188-A1 | Thin membrane for measuring protease activity | Fuji Photo Film Co. Ltd. (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-7067272-B2 | Thin membrane for measuring protease activity | FUJI PHOTO FILM CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| EP-0794218-B1 | Polycarbonate resin composition stabilized against radiation | MITSUBISHI ENG PLASTICS CORP (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-5455218-A | Supported dye layer containing binder and substituted pyrrolopyrazoles, for transferring high density colorfast images | AGFA-GEVAERT N.V. (BE) | 1995-10-03 | — | — | US | disclosed |
| EP-0670225-A1 | A dye donor element for use in a thermal dye transfer process | AGFA-GEVAERT N.V. (BE) | 1995-09-06 | — | — | EP | disclosed |
| US-5432182-A | Inhibitors of gastric acid secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-07-11 | — | — | US | disclosed |
| CN-1100414-A | Preparation of pharmaceutical compound containing novel derivative of leukol | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-03-22 | — | — | CN | disclosed |
| CN-1027368-C | Process for preparing substituted quinoline derivatives | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1995-01-11 | — | — | CN | disclosed |
| EP-0330485-B1 | 4-AMINO-3-ACYL QUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | SmithKline Beecham Intercredit B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |
| CN-1035501-A | PROCESS FOR PREPARING SUBSTITUTED QUINOLINE DERIVATIVES | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-09-13 | — | — | CN | disclosed |
| WO-1989008104-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |
| EP-0330485-A1 | 4-Amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion | SmithKline Beecham Intercredit B.V. (NL) | 1989-08-30 | — | — | EP | disclosed |