Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295728 | 0.98 | EPHX1 (0.43) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 | |
| Bicarbonate SCHEMBL9555189 | 0.90 | EPHX1 (0.47) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 | |
| Trichloroacetic Acid SCHEMBL9636962 | 0.83 | EPHX1 (0.40) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 | |
| SCHEMBL3986172 | 0.74 | PHGDH (0.37) | ALDH1A1KDM4EPHGDHLMNA | |
| SCHEMBL4086315 | 0.73 | PHGDH (0.40) | ALDH1A1CYP3A4KDM4EPHGDHLMNA | |
| SCHEMBL4102397 | 0.72 | EPHX1 (0.39) | EPHX1ALDH1A1KDM4ESIGMAR1CA12 | |
| SCHEMBL1874081 | 0.71 | HTT (0.41) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 | |
| SCHEMBL1426447 | 0.71 | ALDH1A1 (0.54) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 | |
| SCHEMBL9547549 | 0.71 | EPHX1 (0.54) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 | |
| SCHEMBL31349955 | 0.71 | EPHX1 (0.43) | EPHX1SMN1; SMN2ALDH1A1CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |