Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545129 | 0.85 | SIGMAR1 (0.48) | EPHX1KMT2AMEN1SIGMAR1 | |
| SCHEMBL3915506 | 0.76 | SIGMAR1 (0.40) | EPHX1KDM4EALDH1A1ADH1AADH1C | |
| Hydrochloric Acid SCHEMBL9429210 | 0.74 | EPHX1 (0.37) | EPHX1KMT2ASIGMAR1PKM | |
| SCHEMBL3911158 | 0.72 | EPHX1 (0.39) | EPHX1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL3295728 | 0.71 | EPHX1 (0.43) | EPHX1KDM4EALDH1A1CA12CA1 | |
| SCHEMBL10144655 | 0.70 | KMT2A (0.42) | EPHX1KDM4EALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL28004819 | 0.70 | EPHX1 (0.49) | EPHX1KDM4EALDH1A1 | |
| SCHEMBL9462350 | 0.69 | ADH1A (0.47) | ALDH1A1ADH1AADH1CKMT2AMEN1 | |
| SCHEMBL9351634 | 0.69 | EPHX1 (0.51) | EPHX1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL27510927 | 0.68 | EPHX1 (0.52) | EPHX1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |