Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915666 | 0.79 | HTT (0.49) | HTTPOLBEPHX1ALDH1A1CYP3A4 | |
| SCHEMBL3295728 | 0.74 | EPHX1 (0.43) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL3911158 | 0.71 | EPHX1 (0.39) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| Bicarbonate SCHEMBL9555189 | 0.68 | EPHX1 (0.47) | HTTEPHX1ALDH1A1CYP3A4NPC1 | |
| SCHEMBL2606340 | 0.67 | ALOX5 (0.41) | HTTEPHX1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2606357 | 0.67 | ALOX5 (0.41) | HTTEPHX1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4102397 | 0.63 | EPHX1 (0.39) | EPHX1ALDH1A1KDM4EKMT2A | |
| SCHEMBL6157211 | 0.63 | HTT (0.46) | HTTPOLBEPHX1ALDH1A1CYP3A4 | |
| SCHEMBL2740861 | 0.63 | EPHX1 (0.55) | EPHX1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL3073114 | 0.62 | EPHX1 (0.44) | EPHX1ALDH1A1CYP3A4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496612-A1 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND | Lanxess Elastomers B.V. (NL) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054927-A1 | CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND | DSM IP ASSETS B.V. (NL) | 2011-05-12 | — | — | WO | disclosed |