Acetone

Acetone

SCHEMBL391390

CC(C)=O.CC(C)=O.CC(C)=O.CCO

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
LMNA P02545 3/20 0.60
TSHR P16473 2/20 0.60
THPO P40225 1/20 0.55
TDP1 Q9NUW8 2/20 0.54
FFAR3 O14843 3/20 0.43
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
HSD17B10 Q99714 1/20 0.41
TRPA1 O75762 1/20 0.40
CA1 P00915 2/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
CES1 P23141 2/20 0.38
CES2 O00748 1/20 0.38
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL28124784 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL5828252 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL5668865 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL153745 1.00
Acetone SCHEMBL4909337 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL8041533 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL8107245 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL4414746 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL8041534 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1
Acetone SCHEMBL11454886 1.00 ALDH1A1 (0.60) ALDH1A1LMNATSHRTHPOTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US claimed
JP-5092933-A None JP disclosed
JP-5092933-A None JP disclosed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
EP-2357521-B1 Photosensitive conductive film, method of forming a conductive film substrate and method of forming a conductive pattern substrate HITACHI CHEMICAL CO LTD (JP) 2016-11-02 EP disclosed
US-9161442-B2 Photosensitive conductive film, method for forming conductive film, method for forming conductive pattern, and conductive film substrate HITACHI CHEMICAL COMPANY, LTD. (JP) 2015-10-13 US disclosed
US-9120734-B2 Two-step system and method for the production of methyl isobutyl ketone ClearWaterBay Technology, Inc. (US) 2015-09-01 US disclosed
US-9119310-B2 2015-08-25 US disclosed
US-9069128-B2 Opto-electric combined circuit board and electronic devices HITACHI CHEMICAL COMPANY, LTD. (JP) 2015-06-30 US disclosed
US-6054177-A DEPOSITING THERMOPLASTIC RESIN POWDER INBETWEEN INDIVIDUAL FIBERS OF REINFORCING CONTINUOUS FIBER BUNDLE AND SUBSEQUENTLY APPLYING SOLUTION OF BINDER RESIN DISSOLVED IN SOLVENT TO RESULTING REINFORCING CONTINUOUS FIBER BUNDLE, DESOLVENTIZING TOHO RAYON CO., LTD. (JP) 2000-04-25 US disclosed
US-6040115-A THERMALLY IMAGING A THERMOSENSITIVE ELEMENT SUBSTRATE COATED WITH INK REPELLENT POLYMER COMPRISING SILICONE SEGMENTS AND HARD SEGMENTS TO FORM LITHOGRAPHIC PRINTING PLATE DEVELOPABLE WITHOUT WIPING KODAK POLYCHROME GRAPHICS LLC (US) 2000-03-21 US disclosed
US-5858616-A Photosensitive resin composition, photosensitive film and process for preparing fluorescent pattern using the same, and phosphor subjected to surface treatment and process for preparing the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1999-01-12 US disclosed
EP-0768573-A1 Phosphor-containing photosensitive resin composition for use in manufacturing plasma display panel Hitachi Chemical Co., Ltd. (JP) 1997-04-16 EP disclosed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US disclosed
US-5476690-A Pattern formed by electroless plating using a photoresist; developable by aqueous alkaline solution HITACHI CHEMICAL CO., LTD. (JP) 1995-12-19 US disclosed
EP-0630173-A2 Process for preparing printed circuit board Hitachi Chemical Co., Ltd. (JP) 1994-12-21 EP disclosed
JP-H0592933-A SELECTIVE DECOMPOSITION OF TRIACETONE ALCOHOL MITSUBISHI KASEI CORP 1993-04-16 JP disclosed
JP-H0592933-A SELECTIVE DECOMPOSITION OF TRIACETONE ALCOHOL MITSUBISHI KASEI CORP 1993-04-16 JP disclosed
US-4065287-A PESTICIDES, FERTILIZERS, INSECT REPELLANTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-12-27 US disclosed