Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28124784 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL391390 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL5668865 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL153745 | 1.00 | — | — | |
| Acetone SCHEMBL4909337 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL8041533 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL8107245 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL4414746 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL8041534 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL11454886 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223995-B2 | CLEANING AGENT FOR REMOVING PAINT LAYERS ON SURFACES, METHOD FOR MANUFACTURING THE AGENT AND CLEANING METHOD | INTELLIGENT FLUIDS GMBH (DE) | 2024-12-11 | — | — | EP | claimed |
| EP-0522906-B1 | Herbicidal wettable powders and methods of preparation | FRANCAIS PROD IND CFPI (FR) | 1998-08-19 | — | — | EP | claimed |
| US-5374607-A | Filler particles constitute support or carrier for active substance | C F P I (FR) | 1994-12-20 | — | — | US | claimed |
| US-20240319596-A1 | RADIATION-SENSITIVE COMPOSITION, RESIST PATTERN FORMATION METHOD, POLYMER, AND COMPOUND | JSR CORPORATION (JP) | 2024-09-26 | — | — | US | disclosed |
| US-20240294452-A1 | PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF CUMENE | COVESTRO DEUTSCHLAND AG (DE) | 2024-09-05 | — | — | US | disclosed |
| WO-2024100345-A1 | IMPREGNATION LIQUID, METHOD OF TREATMENT WITH SUCH AN IMPREGNATION LIQUID, AND TREATED PART OBTAINED | HYDROMECANIQUE ET FROTTEMENT (FR) | 2024-05-16 | — | — | WO | disclosed |
| US-20240116839-A1 | PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF ACETOPHENONE | COVESTRO DEUTSCHLAND AG (DE) | 2024-04-11 | — | — | US | disclosed |
| US-20240109831-A1 | PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF BENZENE | COVESTRO DEUTSCHLAND AG (DE) | 2024-04-04 | — | — | US | disclosed |
| US-20240076256-A1 | PROCESS FOR PREPARING BISPHENOL A (BPA) IN THE PRESENCE OF ALPHA-METHYLSTYRENE | COVESTRO DEUTSCHLAND AG (DE) | 2024-03-07 | — | — | US | disclosed |
| EP-4163343-A1 | CONDUCTIVE INKS | AGFA-GEVAERT NV (BE) | 2023-04-12 | — | — | EP | disclosed |
| EP-3389896-B1 | A METALLIC NANOPARTICLE DISPERSION | AGFA GEVAERT NV (BE) | 2023-02-22 | — | — | EP | disclosed |
| CN-1534701-A | Electrolyte for electrolytic capacitor | 三洋化成工业株式会社 | 2004-10-06 | — | — | CN | disclosed |
| WO-2003093357-A1 | COATING COMPOSITION FOR MULTIPLE HYDROPHILIC APPLICATIONS | HYDROMER, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| US-20030203991-A1 | Coating composition for multiple hydrophilic applications | HYDROMER, INC. | 2003-10-30 | — | — | US | disclosed |
| CN-1379397-A | Photorecording medium and photorecording method | TDK CORP (JP) | 2002-11-13 | — | — | CN | disclosed |
| CN-1232845-A | Conductive coating composition and antistatic plate | SUMITOMO CHEMICAL CO (JP) | 1999-10-27 | — | — | CN | disclosed |
| EP-0787763-A2 | Adhesive composition for (meth)acrylate copolymers | ATOHAAS HOLDING C.V. (NL) | 1997-08-06 | — | — | EP | disclosed |
| US-5374607-A | Filler particles constitute support or carrier for active substance | C F P I (FR) | 1994-12-20 | — | — | US | disclosed |
| US-4129434-A | Process for forming a metal oxide coating | GLAVERBELL (BE) | 1978-12-12 | — | — | US | disclosed |
| US-3959199-A | Plastic varnish coating with integral self-protecting formulation and process for producing the same | MANDEL CARLOS DUBINOVSKY | 1976-05-25 | — | — | US | disclosed |