Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28124784 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL391390 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL5828252 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL5668865 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL153745 | 1.00 | — | — | |
| Acetone SCHEMBL8041533 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL8107245 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL4414746 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL8041534 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 | |
| Acetone SCHEMBL11454886 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRTHPOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114515808-B | Step-by-step hot extrusion aluminum/magnesium composite cylindrical part with multiple groups of annular inner ribs and forming process thereof | 太原理工大学 | 2023-09-15 | — | — | CN | claimed |
| CN-114515808-A | Step-by-step hot extrusion aluminum/magnesium composite cylindrical part with multiple groups of annular inner ribs and forming process thereof | 太原理工大学 | 2022-05-20 | — | — | CN | claimed |
| CN-107233609-B | Ligustrum-lysozyme anti-infection dressing and preparation method and application thereof | 中国人民解放军第三军医大学第一附属医院 | 2020-06-19 | — | — | CN | claimed |
| CN-110788347-A | Preparation method of large-size-diameter silver nanowires based on traditional polyol reduction method | 江苏大学 | 2020-02-14 | — | — | CN | claimed |
| CN-107233609-A | A kind of cork wood lysozyme anti-infective dressing and preparation method and application | 中国人民解放军第三军医大学第附属医院 | 2017-10-10 | — | — | CN | claimed |
| CN-105355671-B | A kind of wide spectrum high-efficiency solar photovoltaic battery | 浙江昱辉阳光能源江苏有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-105355671-A | Wide-spectrum efficient solar photovoltaic cell | ZHEJIANG RENESOLA ENERGY JIANGSU CO LTD | 2016-02-24 | — | — | CN | claimed |
| CN-102965633-B | Preparation method of M-type barium ferrite film with c-axis vertical film surface orientation | UNIV ELECTRONIC SCIENCE & TECH | 2015-07-08 | — | — | CN | claimed |
| CN-102181828-B | ZnFe2O4Ferrite film preparation method | UNIV ELECTRONIC SCIENCE & TECH | 2013-06-12 | — | — | CN | claimed |
| CN-102965633-A | Preparation method of M-type barium ferrite film with c-axis vertical film surface orientation | UNIV ELECTRONIC SCIENCE & TECH | 2013-03-13 | — | — | CN | claimed |
| CN-118185833-A | Antagonistic bacterial strain bacillus subtilis subspecies and application thereof | 昆明学院 | 2024-06-14 | — | — | CN | disclosed |
| CN-115010615-B | Preparation method of diethylamino hydroxybenzoyl n-hexyl benzoate | 四川沃肯精细化工有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114515808-B | Step-by-step hot extrusion aluminum/magnesium composite cylindrical part with multiple groups of annular inner ribs and forming process thereof | 太原理工大学 | 2023-09-15 | — | — | CN | disclosed |
| WO-2023165243-A1 | TWO-DIMENSIONAL (PEA)2PBX4 NANOSHEET, PREPARATION METHOD THEREFOR, AND USE THEREOF IN ULTRAVIOLET DETECTOR | 中国科学院深圳先进技术研究院 | 2023-09-07 | — | — | WO | disclosed |
| CN-114685555-A | Two dimension (PEA)2PbX4Nanosheet, preparation method and application of nanosheet in ultraviolet light detector | 中国科学院深圳先进技术研究院 | 2022-07-01 | — | — | CN | disclosed |
| CN-102181828-A | ZnFe2O4Ferrite film preparation method | UNIV ELECTRONIC SCIENCE & TECH | 2011-09-14 | — | — | CN | disclosed |
| US-20080293975-A1 | Method of Recovering Xanthophyll | YAMAHA HATSUDOKI KABUSHIKI KAISHA (JP) | 2008-11-27 | — | — | US | disclosed |
| US-20080018238-A1 | Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-24 | — | — | US | disclosed |
| EP-1852417-A1 | METHOD OF RECOVERING XANTHOPHYLL | YAMAHA HATSUDOKI KABUSHIKI KAISHA (JP) | 2007-11-07 | — | — | EP | disclosed |
| CN-1956950-A | Method of recovering xanthophyll | YAMAHA MOTOR CO LTD (JP) | 2007-05-02 | — | — | CN | disclosed |