Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31011017 | 1.00 | HPGD (0.61) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| Bicarbonate SCHEMBL236924 | 0.98 | GABRA1 (0.59) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL1039957 | 0.86 | ALDH1A1 (0.55) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL2164384 | 0.86 | HPGD (0.46) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL31123826 | 0.86 | GABRA1 (0.64) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL8680640 | 0.86 | GABRA1 (0.64) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL10603918 | 0.85 | ALDH1A1 (0.53) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL29484676 | 0.84 | GABRA1 (0.61) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL20853605 | 0.84 | GABRA1 (0.61) | HPGDGABRA1CYP3A4GABRB1CA1 | |
| SCHEMBL429128 | 0.84 | GABRA1 (0.61) | HPGDGABRA1CYP3A4GABRB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1074 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| CN-113677319-A | Increasing the stability of agents for treating keratin materials | 汉高股份有限及两合公司 | 2021-11-19 | — | — | CN | claimed |
| EP-3484970-A1 | COMPOSITION FOR SILICONE RUBBER MATERIALS | Nitrochemie Aschau GmbH (DE) | 2019-05-22 | — | — | EP | claimed |
| EP-2773729-B1 | THE USE OF QUATERNIZED POLYETHERAMINES AS ADDITIVES IN FUELS AND LUBRICANTS | BASF SE (DE) | 2019-02-13 | — | — | EP | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| EP-1414779-B1 | SOLVENTLESS PREPARATION OF ESTER-SUBSTITUTED DIARYL CARBONATES | SABIC INNOVATIVE PLASTICS IP (NL) | 2015-05-27 | — | — | EP | claimed |
| EP-1963398-B1 | EQUIPMENT CLEANING IN THE MANUFACTURE OF POLYCARBONATES | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-03-30 | — | — | EP | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| EP-1722859-B1 | A BASE COMPOSITION FOR PREPARING MULTI-FUNCTIONAL FORMULATIONS FOR CARE AND PROTECTION OF THE SKIN AND HAIR | NATURA COSMETICOS SA (BR) | 2010-09-08 | — | — | EP | claimed |
| EP-1414780-B1 | INTERFACIAL METHOD OF PREPARING ESTER-SUBSTITUTED DIARYL CARBONATES | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-08-26 | — | — | EP | claimed |
| US-6398857-B1 | ACCUSTIC PIEZOELECTRIC; HOT MELT INK JET PRINTING; BENZOIC ACID VEHICLE; ALKYL OR PHENYL CARBOXYLIC ACID VISCOSITY MODIFIER; RETAINS DESIRED HARDNESS | XEROX CORPORATION | 2002-06-04 | — | — | US | claimed |
| US-5683793-A | Ink jet transparencies | XEROX CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| US-4638340-A | PROTECTIVE AND DECOLORING INTERMEDIATE LAYERS TO PRODUCE SEPARATE AND DISTINCT COLOR | RICOH COMPANY, LTD. (JP) | 1987-01-20 | — | — | US | claimed |
| US-4636819-A | SUPPORT, LEUCO DYE, DEVELOPER, WATER SOLUBLE RESIN | RICOH COMPANY, LTD. (JP) | 1987-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | HPGD 3676/4885GABRA1 4353/4885CYP3A4 4051/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | HPGD 3676/4885GABRA1 4353/4885CYP3A4 4051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.