Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3915156 | 0.98 | KDM4E (0.53) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL6294366 | 0.90 | LCK (0.58) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL3917252 | 0.88 | PTPN11 (0.60) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL3915151 | 0.86 | LCK (0.47) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL3917214 | 0.86 | LCK (0.65) | KDM4EPTPN11LCKCA12CA1 | |
| Hydrochloric Acid SCHEMBL3914484 | 0.86 | PTPN11 (0.59) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL3914443 | 0.84 | HRH3 (0.52) | KDM4EPTPN11CA12CA1CA2 | |
| SCHEMBL29812614 | 0.83 | LCK (0.53) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL30570062 | 0.83 | LCK (0.53) | KDM4EPTPN11LCKCA12CA1 | |
| SCHEMBL5541003 | 0.83 | LCK (0.53) | KDM4EPTPN11LCKCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531691-B2 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1867629-A2 | Method for producing naphthalene carboxylic acid amide compound | Ueno Fine Chemicals Industry, Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| CN-101088987-A | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICAL IND (JP) | 2007-12-19 | — | — | CN | disclosed |
| US-7169523-B2 | electrophotographic toners comprising binder resins, colorants and charge control agents consisting of naphthol derivatives, having excellent negative chargeability, dispersion in and compatibility with binders | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2007-01-30 | — | — | US | disclosed |
| CN-1860096-A | Aminocarbonyl naphthol derivative, cyanonaphthol derivative and preparation method thereof | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2006-11-08 | — | — | CN | disclosed |
| US-20060231589-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2006-10-19 | — | — | US | disclosed |
| EP-1712546-A1 | Hydroxynaphthalenedicarboxylic acid hydrazide and derivatives thereof as well as process for preparing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-20060205952-A1 | Aminocarbonyl naphthol derivative, cyanonaphthol derivative, and method for producing them | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-1048694-B1 | AZO COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-20020151720-A1 | NAPHTHOL DERIVATIVES | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-10-17 | — | — | US | disclosed |
| US-6451988-B1 | AN AZO COMPOUND AND A METAL COMPLEX WHICH ARE SYNTHESIZED WITH THE NAPHTHOL DERIVATIVE | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-09-17 | — | — | US | disclosed |
| US-6409812-B1 | MONOAZO DYE; PAINTS, INK JETS, COLOR FILTERS; ELECTROGRAPHY; DIAZOTIZATION | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6388045-B1 | CARBOXYLATED AROMATIC COMPOUND | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1103573-A1 | LIQUID-CRYSTAL POLYMER | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-05-30 | — | — | EP | disclosed |
| CN-1291215-A | Toning agent | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2001-04-11 | — | — | CN | disclosed |
| EP-1048694-A1 | AZO COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-1043364-A1 | TONING AGENT | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-6005085-A | NOVEL CONDENSED AZO COMPOUNDS USING BISAMIDE COMPOUNDS OF 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID, AMIDE, OR ESTER AS THE COUPLERS, WHICH HAVE EXCELLENT PROPERTIES SUCH AS EXCELLENT WATER RESISTANCE, CHEMICAL RESISTANCE, SOLVENT | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0913430-A1 | CONDENSED AZO COMPOUND AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1999-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151720-A1 | NAPHTHOL DERIVATIVES | NAP1L1, IK, NAP1L4 | KDM4E 3584/4885PTPN11 1039/4885LCK 1281/4885 |
| US-20060205952-A1 | Aminocarbonyl naphthol derivative, cyanonaphthol derivative, and method for producing them | HCCS, CYP8B1, NCAPD3 | KDM4E 1918/4885PTPN11 2939/4885LCK 3212/4885 |
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | NAAA, AADAC, NAT1 | KDM4E 2012/4885PTPN11 2986/4885LCK 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.