Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294366 | 0.89 | LCK (0.58) | LCKCA12CA1CA2CA7 | |
| SCHEMBL3914476 | 0.88 | LCK (0.54) | LCKCA12CA1CA2CA7 | |
| SCHEMBL3914142 | 0.86 | KDM4E (0.54) | LCKCA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL3915156 | 0.85 | KDM4E (0.53) | LCKCA12CA1CA2CA7 | |
| SCHEMBL3917214 | 0.85 | LCK (0.65) | LCKCA12CA1CA2CA7 | |
| SCHEMBL3924193 | 0.84 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3924507 | 0.84 | LCK (0.52) | LCKGAAMEN1KMT2AMAPT | |
| SCHEMBL20414588 | 0.82 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30362293 | 0.82 | PTPN11 (0.58) | LCKCA12CA1CA2CA7 | |
| SCHEMBL4498737 | 0.82 | PTPN11 (0.58) | LCKCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531691-B2 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICALS INDUSTRY, LTD. (JP) | 2008-02-21 | — | — | US | disclosed |
| EP-1867629-A2 | Method for producing naphthalene carboxylic acid amide compound | Ueno Fine Chemicals Industry, Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| CN-101088987-A | Method for producing naphthalene carboxylic acid amide compound | UENO FINE CHEMICAL IND (JP) | 2007-12-19 | — | — | CN | disclosed |
| EP-0872477-B1 | NAPHTHOL DERIVATIVE AND PROCESS FOR PREPARING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6084101-A | Naphtol derivative and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0872477-A1 | NAPHTHOL DERIVATIVE AND PROCESS FOR PREPARING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045720-A1 | Method for producing naphthalene carboxylic acid amide compound | NAAA, AADAC, NAT1 | LCK 4052/4885CA12 83/4885CA1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.