Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA7 | P43166 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.56 |
| ▸ | XDH | P47989 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917252 | 0.90 | PTPN11 (0.60) | LCKCA1CA2CA12CA7 | |
| SCHEMBL3914142 | 0.90 | KDM4E (0.54) | LCKCA1CA2CA12CA7 | |
| SCHEMBL30151494 | 0.90 | PTPN11 (0.58) | LCKCA1CA2CA12CA7 | |
| SCHEMBL23692611 | 0.90 | CA1 (0.69) | LCKCA1CA2CA12CA7 | |
| SCHEMBL3915151 | 0.89 | LCK (0.47) | LCKCA1CA2CA12CA7 | |
| SCHEMBL5695677 | 0.89 | LCK (0.56) | LCKCA1CA2CA12CA7 | |
| SCHEMBL3917214 | 0.89 | LCK (0.65) | LCKCA1CA2CA12CA7 | |
| SCHEMBL3914476 | 0.89 | LCK (0.54) | LCKCA1CA2CA12CA7 | |
| Hydrochloric Acid SCHEMBL3914484 | 0.89 | PTPN11 (0.59) | LCKCA1CA2CA12CA7 | |
| Hydrochloric Acid SCHEMBL3915156 | 0.89 | KDM4E (0.53) | LCKCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401435-A1 | MRGPRX2 ANTAGONIST FOR THE TREATMENT OF PSEUDO ALLERGIC REACTIONS | THE UNIVERSITY OF HONG KONG | 2022-12-22 | — | — | US | disclosed |
| CN-1246287-C | Binaphthol derivative and method for producing same | UENO SEIYAKU OYO KENKYUSHO K K (JP) | 2006-03-22 | — | — | CN | disclosed |
| US-6849742-B2 | Binaphthol derivative and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-02-01 | — | — | US | disclosed |
| EP-1103573-B1 | LIQUID-CRYSTAL POLYMER | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2004-09-15 | — | — | EP | disclosed |
| CN-1163548-C | Toning agent | 株式会社上野制药应用研究所 | 2004-08-25 | — | — | CN | disclosed |
| US-20040063963-A1 | Binaphthol derivative and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1380564-A1 | BINAPHTOL DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 2004-01-14 | — | — | EP | disclosed |
| CN-1463266-A | Binaphthol derivative and method for producing same | UENO SEIYAKU OYO KENKYUSHO K K (JP) | 2003-12-24 | — | — | CN | disclosed |
| US-6548703-B1 | Toning agent | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-1095930-B1 | NOVEL COMPOUNDS | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-6284924-B1 | BIS/OXYNAPHTHALENE DERIVATIVES OF CARBOXYLIC ACIDS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKUJO (JP) | 2001-09-04 | — | — | US | disclosed |
| US-6252104-B1 | 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-1103573-A1 | LIQUID-CRYSTAL POLYMER | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-1095930-A1 | NOVEL COMPOUNDS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-05-02 | — | — | EP | disclosed |
| CN-1291215-A | Toning agent | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2001-04-11 | — | — | CN | disclosed |
| EP-1043364-A1 | TONING AGENT | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0765858-B1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5847233-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5786523-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0765858-A1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1997-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401435-A1 | MRGPRX2 ANTAGONIST FOR THE TREATMENT OF PSEUDO ALLERGIC REACTIONS | MRGPRX2, MRGPRX1, MRGPRX4 | LCK 4022/4885CA1 3078/4885CA2 1700/4885 |
| US-20040063963-A1 | Binaphthol derivative and process for producing the same | CYP46A1, CYP21A2, CYP17A1 | LCK 4113/4885CA1 2086/4885CA2 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.