Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914151 | 0.83 | IDO1 (0.51) | ALDH1A1HTTTP53IDO1MAPK1 | |
| SCHEMBL3925390 | 0.78 | ERCC5 (0.42) | ALDH1A1HTTDGAT1IDO1MAPT | |
| SCHEMBL2951923 | 0.77 | PYCR1 (0.41) | ALDH1A1HTTLMNAPYCR1SMN1; SMN2 | |
| SCHEMBL480186 | 0.77 | PYCR1 (0.42) | ALDH1A1HTTLMNAPYCR1NPC1 | |
| SCHEMBL8173928 | 0.73 | LMNA (0.43) | ALDH1A1HTTLMNAPYCR1NPC1 | |
| SCHEMBL16827451 | 0.72 | PYCR1 (0.43) | ALDH1A1HTTLMNAPYCR1HPGD | |
| SCHEMBL29899638 | 0.72 | GRIK1 (0.46) | PYCR1MGAMGAASIMGAM2 | |
| SCHEMBL473923 | 0.72 | GRIK1 (0.46) | PYCR1MGAMGAASIMGAM2 | |
| SCHEMBL1328959 | 0.71 | DGAT1 (0.60) | ALDH1A1SMN1; SMN2TSHRKMT2ADGAT1 | |
| SCHEMBL27849373 | 0.70 | PYCR1 (0.41) | ALDH1A1HTTLMNAPYCR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035374-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | Syngeta Participations AG (CH) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007141009-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-13 | — | — | WO | disclosed |