Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314893 | 1.00 | NR3C1 (0.35) | NR3C1ALDH1A1LMNAESR1PGR | |
| SCHEMBL3914283 | 1.00 | NR3C1 (0.35) | NR3C1ALDH1A1LMNAESR1PGR | |
| SCHEMBL8133320 | 0.78 | SLC6A1 (0.33) | SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL9823369 | 0.78 | SLC6A1 (0.33) | NR3C1SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL9823374 | 0.78 | SLC6A1 (0.33) | NR3C1SLC6A1SLC6A12SLC6A11 | |
| Acrylic Acid SCHEMBL29061738 | 0.76 | GPBAR1 (0.31) | ALDH1A1GPBAR1 | |
| Acrylic Acid SCHEMBL29061734 | 0.76 | GPBAR1 (0.31) | ALDH1A1GPBAR1 | |
| SCHEMBL6949185 | 0.76 | SLC6A1 (0.30) | SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL7755842 | 0.76 | GPBAR1 (0.34) | GPBAR1SLC6A1SLC6A12SLC6A11 | |
| SCHEMBL8755099 | 0.75 | SLC6A1 (0.31) | SLC6A1SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835902-B1 | SPIRO[BORNYL-2,4'-(1,3-DIOXANES)] AND THEIR USES AS FRAGRANCE INGREDIENTS | GIVAUDAN SA (CH) | 2009-03-11 | — | — | EP | disclosed |
| US-20080161223-A1 | Spirobornyl-2,4-(1,3-Dioxanes)] And Their Uses As Fragrance Ingredients | GIVAUDAN SA (CH) | 2008-07-03 | — | — | US | disclosed |
| EP-1835902-A2 | SPIRO[BORNYL-2,4'-(1,3-DIOXANES)] AND THEIR USES AS FRAGRANCE INGREDIENTS | Givaudan SA (CH) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006072189-A2 | SPIRO [BORNYL - 2 , 4' - ( 1 , 3 -DIOXANES) ] AND THEIR USES AS FRAGRANCE INGREDIENTS | GIVAUDAN SA (CH) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161223-A1 | Spirobornyl-2,4-(1,3-Dioxanes)] And Their Uses As Fragrance Ingredients | TRPA1, TRPV1, SRD5A1 | NR3C1 1352/4885ALDH1A1 14/4885LMNA 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.