SCHEMBL3914396

SCHEMBL3914396

Cn1c(Br)cnc1C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3953092 0.76
SCHEMBL9638546 0.74
SCHEMBL22035326 0.74 PTGER4 (0.36)
SCHEMBL15507325 0.74 KDM4E (0.42)
SCHEMBL16968066 0.74 KDM4E (0.42)
SCHEMBL23235966 0.69 MEN1 (0.36)
SCHEMBL17260754 0.69 KDM4E (0.31)
SCHEMBL15707248 0.69
SCHEMBL8538434 0.68 LMNA (0.44)
SCHEMBL27396039 0.68 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605451-B2 Targeted plasma protein degradation NOVARTIS AG (CH) 2026-04-21 US disclosed
US-12528781-B2 Heterocyclic GLP-1 agonists GASHERBRUM BIO, INC. (US) 2026-01-20 US disclosed
EP-4192831-B1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO INC (US) 2025-10-22 EP disclosed
CN-115279761-B Crystal of imidazopyridone compound or salt thereof 橘生药品工业株式会社 2025-03-14 CN disclosed
CN-113166114-B Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders 诺华股份有限公司 2025-01-03 CN disclosed
US-20240425504-A1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (assignee) (JP) 2024-12-26 US disclosed
EP-3808747-B1 IMIDAZOPYRIDINONE COMPOUND KISSEI PHARMACEUTICAL (JP) 2024-12-18 EP disclosed
US-20240376061-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. 2024-11-14 US disclosed
US-12077531-B2 Imidazopyridinone compound KISSEI PHARMACEUTICAL CO., LTD. (JP) 2024-09-03 US disclosed
WO-2024130095-A9 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-02 WO disclosed
US-20100331315-A1 RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS SENHWA BIOSCIENCES, INC. (TW) 2010-12-30 US disclosed
US-20100331315-A1 RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS SENHWA BIOSCIENCES, INC. (TW) 2010-12-30 US disclosed
WO-2010148351-A1 RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS CYLENE PHARMACEUTICALS, INC. (US) 2010-12-23 WO disclosed
WO-2010007756-A1 PYRIDINE DERIVATIVE HAVING TTK INHIBITION ACTIVITY 塩野義製薬株式会社 (JP) 2010-01-21 WO disclosed
EP-2021381-A2 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-02-11 EP disclosed
EP-2018390-A2 ORTHO-METALLATED HAFNIUM COMPLEXES OF IMIDAZOLE LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-01-28 EP disclosed
EP-2018391-A2 IMPROVED HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-01-28 EP disclosed
WO-2007130306-A2 ORTHO-METALLATED HAFNIUM COMPLEXES OF IMIDAZOLE LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-15 WO disclosed
WO-2007130242-A2 HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-15 WO disclosed
WO-2007130307-A2 IMPROVED HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-15 WO disclosed