Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 5/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910231 | 0.81 | LAP3 (0.41) | SLC1A2SLC1A1SLC1A3ENPEPSLC7A5 | |
| SCHEMBL1529632 | 0.76 | ALPI (0.47) | SLC1A2SLC1A1SLC1A3SLC7A5PTGS1 | |
| SCHEMBL793417 | 0.74 | GABRR1 (0.33) | SLC1A2SLC1A1SLC1A3SLC7A5ALDH1A1 | |
| SCHEMBL10830748 | 0.72 | CHRM1 (0.44) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1069360 | 0.72 | OR51E2 (0.33) | — | |
| SCHEMBL4595646 | 0.72 | MME (0.34) | ALDH1A1CA2 | |
| SCHEMBL1529741 | 0.71 | GRM2 (0.41) | — | |
| SCHEMBL23855055 | 0.71 | TGFBR1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL394954 | 0.71 | TGFBR1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL657408 | 0.71 | GABRR1 (0.45) | ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797065-A4 | ACYCLIC 1,3-DIAMINES AND USES THEREFOR | SMITHKLINE BEECHAM CORP (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1797065-A2 | ACYCLIC 1,3-DIAMINES AND USES THEREFOR | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006029210-A2 | ACYCLIC 1,3-DIAMINES AND USES THEREFOR | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |