Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 8/20 | 0.40 |
| ▸ | CA2 | P00918 | 8/20 | 0.40 |
| ▸ | CA9 | Q16790 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26144 | 1.00 | DNM1 (0.48) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL931394 | 1.00 | DNM1 (0.48) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL887114 | 1.00 | DNM1 (0.48) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL246013 | 1.00 | DNM1 (0.48) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL28795866 | 0.96 | DNM1 (0.45) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL27515670 | 0.96 | DNM1 (0.45) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL26629020 | 0.94 | DNM1 (0.44) | DNM1CA1CA2CA9CA12 | |
| SCHEMBL9302688 | 0.90 | ADRB2 (0.38) | DNM1CA1CA2CA9TSHR | |
| SCHEMBL2701156 | 0.88 | ALDH1A1 (0.51) | LPAR1LPAR3LPAR2 | |
| SCHEMBL27503005 | 0.86 | ADRB2 (0.35) | DNM1CA1CA2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251497-A | Lipid compositions comprising peptide-lipid conjugates | 阿克丘勒斯治疗公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118201639-A | Peptide-lipid conjugates | 阿克丘勒斯治疗公司 | 2024-06-14 | — | — | CN | claimed |
| EP-4333898-A2 | PEPTIDE-LIPID CONJUGATES | Arcturus Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | claimed |
| EP-4334455-A1 | LIPID COMPOSITIONS COMPRISING PEPTIDE-LIPID CONJUGATES | Arcturus Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | claimed |
| EP-4305051-A1 | CHIMERIC PROTEINS IN AUTOIMMUNITY | Shattuck Labs, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| WO-2023077156-A1 | MODIFIED MRNA THERAPEUTICS | SHATTUCK LABS, INC. (US) | 2023-05-04 | — | — | WO | claimed |
| EP-3634449-A1 | ALPHAVIRUS NEOANTIGEN VECTORS | Gritstone Oncology, Inc. (US) | 2020-04-15 | — | — | EP | claimed |
| WO-2018208856-A1 | ALPHAVIRUS NEOANTIGEN VECTORS | GRITSTONE ONCOLOGY, INC. (US) | 2018-11-15 | — | — | WO | claimed |
| CN-108350455-A | COMPOSITIONS AND METHODS FOR SILENCING HEPATITIS B VIRUS GENE EXPRESSION | 阿布特斯生物制药公司 | 2018-07-31 | — | — | CN | claimed |
| EP-3329003-A2 | COMPOSITIONS AND METHODS FOR SILENCING HEPATITIS B VIRUS GENE EXPRESSION | Arbutus Biopharma Corporation (CA) | 2018-06-06 | — | — | EP | claimed |
| EP-2764007-A1 | COMPOSITIONS AND METHODS FOR SILENCING ALDEHYDE DEHYDROGENASE | Protiva Biotherapeutics Inc. (CA) | 2014-08-13 | — | — | EP | claimed |
| WO-2013052677-A1 | COMPOSITIONS AND METHODS FOR SILENCING ALDEHYDE DEHYDROGENASE | PROTIVA BIOTHERAPEUTICS INC. (CA) | 2013-04-11 | — | — | WO | claimed |
| EP-1828219-A1 | SIRNA SILENCING OF APOLIPOPROTEIN B | Protiva Biotherapeutics Inc. (CA) | 2007-09-05 | — | — | EP | claimed |
| WO-2007048046-A9 | SIRNA SILENCING OF FILOVIRUS GENE EXPRESSION | PROTIVA BIOTHERAPEUTICS INC (CA) | 2007-06-14 | — | — | WO | claimed |
| WO-2007056861-A1 | SIRNA SILENCING OF INFLUENZA VIRUS GENE EXPRESSION | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2007-05-24 | — | — | WO | claimed |
| WO-2007048046-A2 | SIRNA SILENCING OF FILOVIRUS GENE EXPRESSION | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2007-04-26 | — | — | WO | claimed |
| EP-1773857-A1 | IMMUNOSTIMULATORY SIRNA MOLECULES AND USES THEREFOR | Protiva Biotherapeutics Inc. (CA) | 2007-04-18 | — | — | EP | claimed |
| WO-2006074546-A1 | LIPID ENCAPSULATED INTERFERING RNA | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2006-07-20 | — | — | WO | claimed |
| WO-2006053430-A1 | SIRNA SILENCING OF APOLIPOPROTEIN B | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2006-05-26 | — | — | WO | claimed |
| WO-2006002538-A1 | IMMUNOSTIMULATORY SIRNA MOLECULES AND USES THEREFOR | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2006-01-12 | — | — | WO | claimed |