Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CDA | P32320 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13715908 | 1.00 | LMNA (0.46) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL3915248 | 1.00 | LMNA (0.46) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL24024879 | 0.94 | LMNA (0.43) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL24024883 | 0.94 | LMNA (0.43) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL24024770 | 0.93 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL21970361 | 0.93 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14727467 | 0.93 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL24024592 | 0.93 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL15850638 | 0.93 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18902462 | 0.93 | LMNA (0.41) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569685-B2 | Artificial RNAóS modified at the 2ó-hydroxyl group | JAPAN SCIENCCE AND TECHNOLOGY AGENCY (JP) | 2009-08-04 | — | — | US | claimed |
| US-20080021206-A1 | Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-01-24 | — | — | US | claimed |
| EP-1726597-A1 | NOVEL ARTIFICIAL RNAóS MODIFIED AT THE 2ó-HYDROXYL GROUP | Japan Science and Technology Agency (JP) | 2006-11-29 | — | — | EP | claimed |
| US-7569685-B2 | Artificial RNAóS modified at the 2ó-hydroxyl group | JAPAN SCIENCCE AND TECHNOLOGY AGENCY (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080021206-A1 | Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1726597-A1 | NOVEL ARTIFICIAL RNAóS MODIFIED AT THE 2ó-HYDROXYL GROUP | Japan Science and Technology Agency (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021206-A1 | Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group | FBL, NSUN2, METTL16 | LMNA 567/4885MTOR 3400/4885THRB 3879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.