Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386724 | 0.82 | ALDH1A1 (0.75) | GAAALDH1A1SIGMAR1LMNAHPGD | |
| SCHEMBL3156389 | 0.79 | GAA (0.83) | GAAALDH1A1SIGMAR1LMNAHPGD | |
| SCHEMBL9577239 | 0.79 | SIGMAR1 (0.68) | GAAALDH1A1SIGMAR1 | |
| SCHEMBL3153289 | 0.79 | SIGMAR1 (0.59) | GAAALDH1A1SIGMAR1RAB9AHTT | |
| SCHEMBL3019231 | 0.76 | SIGMAR1 (0.70) | GAAALDH1A1SIGMAR1 | |
| SCHEMBL23476689 | 0.75 | ALDH1A1 (0.59) | GAAALDH1A1SIGMAR1LMNAHPGD | |
| SCHEMBL14303888 | 0.75 | SIGMAR1 (0.63) | GAAALDH1A1SIGMAR1LMNA | |
| SCHEMBL2934786 | 0.75 | ALDH1A1 (0.67) | GAAALDH1A1SIGMAR1HPGDTSHR | |
| SCHEMBL1892301 | 0.75 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDRAB9AKDM4E | |
| SCHEMBL18377408 | 0.74 | SIGMAR1 (0.67) | GAAALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035372-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008005338-A1 | MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2008-01-10 | — | — | WO | disclosed |