Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 2/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | MMP7 | P09237 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303888 | 0.90 | SIGMAR1 (0.63) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL18377408 | 0.90 | SIGMAR1 (0.67) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL9780583 | 0.90 | ALDH1A1 (0.67) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL15145875 | 0.88 | CYP3A4 (0.70) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL3019231 | 0.88 | SIGMAR1 (0.70) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL1348420 | 0.88 | ALDH1A1 (0.64) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL3412674 | 0.86 | MMP1 (0.58) | SIGMAR1GAAMMP1MMP2MMP9 | |
| SCHEMBL15145874 | 0.85 | GAA (0.60) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL5435010 | 0.85 | GAA (0.60) | SIGMAR1GAACYP19A1MMP1MMP2 | |
| SCHEMBL8578107 | 0.85 | GAA (0.69) | SIGMAR1GAACA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4957958-A | IMPROVED MELT FLOW | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |