Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | SELL | P14151 | 1/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | SELE | P16581 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090217 | 1.00 | ACHE (0.65) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL69718 | 0.80 | ACHE (1.00) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL5778579 | 0.80 | ACHE (0.40) | ACHESELLSELPSELEALDH1A1 | |
| SCHEMBL11136759 | 0.79 | CYP3A4 (0.50) | ACHEESR1ESR2CYP3A4MAPT | |
| SCHEMBL11418582 | 0.79 | SELL (0.65) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL22112316 | 0.76 | ACHE (0.46) | ACHESELLSELPSELEALDH1A1 | |
| SCHEMBL24701452 | 0.75 | GAA (0.46) | ACHEALDH1A1ESR2CYP3A4KDM4E | |
| SCHEMBL22265090 | 0.75 | ALDH1A1 (0.41) | ACHEALDH1A1CYP3A4MAPTKMT2A | |
| SCHEMBL21614390 | 0.75 | SELL (0.46) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL22690036 | 0.75 | ACHE (0.40) | ACHEALDH1A1CYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842410-A1 | FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF | Beijing Wholesomeyird Sci & Tech Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038464-A1 | FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF | 北京厚燊药德科技有限责任公司 | 2020-02-27 | — | — | WO | disclosed |
| EP-2024353-A2 | PYRAZOLE COMPOUNDS | Pfizer Products Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007105058-A2 | PYRAZOLE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007105058-A2 | PYRAZOLE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |