SCHEMBL11136759

SCHEMBL11136759

Cc1c(O)cc(Br)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALOX15 P16050 5/20 0.48
ALOX12 P18054 3/20 0.48
LMNA P02545 3/20 0.45
HPGD P15428 2/20 0.45
HTT P42858 2/20 0.45
PRNP P04156 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NOD2 Q9HC29 1/20 0.45
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
ACHE P22303 1/20 0.43
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9744264 0.86 ACHE (0.58) CYP3A4TSHRTDP1ALOX15ALOX12
SCHEMBL642403 0.80 TSHR (0.47) CYP3A4TSHRTDP1ALOX15ALOX12
SCHEMBL30885796 0.79 ACHE (0.43) CYP3A4TSHRTDP1ALOX15ALOX12
SCHEMBL6670488 0.79 ACHE (0.43) CYP3A4TSHRTDP1ALOX15ALOX12
SCHEMBL3915772 0.79 ACHE (0.65) CYP3A4TDP1ALOX15ALOX12LMNA
SCHEMBL31090217 0.79 ACHE (0.65) CYP3A4TDP1ALOX15ALOX12LMNA
SCHEMBL22112316 0.76 ACHE (0.46) CYP3A4TSHRTDP1ALOX15ALOX12
SCHEMBL24701452 0.75 GAA (0.46) CYP3A4TSHRTDP1ALOX15LMNA
SCHEMBL22690036 0.75 ACHE (0.40) CYP3A4ALOX15LMNAHPGDHTT
SCHEMBL22265090 0.75 ALDH1A1 (0.41) CYP3A4TSHRTDP1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9410088-B2 Phosphonate-substituted lignin as a flame retardant EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-08-09 US disclosed
CN-103012196-B 2- [ (2-hydroxy) -benzylimino ] methylphenol complex and preparation and application thereof PETROCHINA COMPANY LIMITED (CN) 2015-09-23 CN disclosed
US-8962779-B2 Method of forming polyaryl polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-24 US disclosed
US-20150031847-A1 METHOD OF FORMING POLYARYL POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2015-01-29 US disclosed
US-20140378671-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT CRESTLINE DIRECT FINANCE, L.P. 2014-12-25 US disclosed
US-8852468-B2 Phosphonate-substituted lignin as a flame retardant EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-10-07 US disclosed
US-20140235132-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-08-21 US disclosed
US-8747709-B2 Phosphonate-substituted lignin as a flame retardant EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-06-10 US disclosed
WO-2013165425-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-11-07 WO disclosed
US-20130292615-A1 PHOSPHONATE-SUBSTITUTED LIGNIN AS A FLAME RETARDANT EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-11-07 US disclosed
CN-103012196-A 2- [ (2-hydroxy) -benzylimino ] methylphenol complex and preparation and application thereof PETROCHINA CO LTD 2013-04-03 CN disclosed
US-4420552-A Method of producing printed images with a color facsimile printing device Peck, Richard M. (US) 1983-12-13 US disclosed
US-4390614-A Color facsimile printing device comprising photosensitive ink in pores Peck, Richard M. (US) 1983-06-28 US disclosed