Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.40 |
| ▸ | CES2 | O00748 | 6/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915868 | 1.00 | CES1 (0.40) | CES1CES2TRPA1ALDH1A1TP53 | |
| SCHEMBL20942862 | 0.95 | CES1 (0.43) | CES1CES2TRPA1ALDH1A1TP53 | |
| SCHEMBL20942916 | 0.90 | CES2 (0.38) | CES1CES2TRPA1ALDH1A1MAPT | |
| SCHEMBL1701354 | 0.88 | CES2 (0.46) | CES1CES2TRPA1ALDH1A1TSHR | |
| SCHEMBL1701125 | 0.88 | CES2 (0.46) | CES1CES2TRPA1ALDH1A1TSHR | |
| SCHEMBL6627036 | 0.88 | TRPA1 (0.48) | CES1CES2TRPA1ALDH1A1MAPT | |
| SCHEMBL16012618 | 0.86 | CES2 (0.48) | CES1CES2TRPA1ALDH1A1TSHR | |
| SCHEMBL16012600 | 0.86 | CES2 (0.48) | CES1CES2TRPA1ALDH1A1TSHR | |
| SCHEMBL31647623 | 0.86 | CES2 (0.48) | CES1CES2TRPA1ALDH1A1TSHR | |
| SCHEMBL4136048 | 0.86 | CES1 (0.40) | CES1CES2TRPA1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032516-B1 | FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2012-09-26 | — | — | EP | claimed |
| US-20090202464-A1 | Fragrance Compounds | GIVAUDAN S.A. (CH) | 2009-08-13 | — | — | US | claimed |
| EP-2032516-A1 | FRAGRANCE COMPOUNDS | Givaudan SA (CH) | 2009-03-11 | — | — | EP | claimed |
| WO-2007143873-A1 | FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-12-21 | — | — | WO | claimed |
| EP-0953562-A1 | Beta, gamma-unsaturated delta-keto esters | Givaudan Roure (International) S.A. (CH) | 1999-11-03 | — | — | EP | claimed |
| US-5831135-A | CATALYST SELECTIVITY; PURITY | HUELS AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | claimed |
| US-5675045-A | Process for the catalytic selective hydrogenation of polyunsaturated organic substances | HUELS AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | claimed |
| EP-0753496-A2 | Process for the catalytic selective hydrogenation of multiple unsaturated organic substances | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-01-15 | — | — | EP | claimed |
| US-10946304-B2 | Process for recovering aldehyde obtained by hydroformulation in two columns with increasing pressure | JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) | 2021-03-16 | — | — | US | disclosed |
| US-20200298138-A1 | PROCESS FOR RECOVERING ALDEHYDE OBTAINED BY HYDROFORMULATION IN TWO COLUMNS WITH INCREASING PRESSURE | JOHNSON MATTHEY DAVY TECHNOLOGIES LIMITED (GB) | 2020-09-24 | — | — | US | disclosed |
| EP-3544950-A1 | PRECURSOR COMPOUNDS FOR FRAGRANT ALDEHYDES | Givaudan S.A. (CH) | 2019-10-02 | — | — | EP | disclosed |
| US-20190276387-A1 | PRECURSOR COMPOUNDS FOR FRAGRANT ALDEHYDES | GIVAUDAN SA (CH) | 2019-09-12 | — | — | US | disclosed |
| WO-2018096176-A1 | PRECURSOR COMPOUNDS FOR FRAGRANT ALDEHYDES | GIVAUDAN SA (CH) | 2018-05-31 | — | — | WO | disclosed |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | US | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |
| EP-0953562-A1 | Beta, gamma-unsaturated delta-keto esters | Givaudan Roure (International) S.A. (CH) | 1999-11-03 | — | — | EP | disclosed |
| EP-0952142-A1 | Compounds with protected hydroxy groups | Givaudan Roure (International) S.A. (CH) | 1999-10-27 | — | — | EP | disclosed |
| US-5831135-A | CATALYST SELECTIVITY; PURITY | HUELS AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| US-5675045-A | Process for the catalytic selective hydrogenation of polyunsaturated organic substances | HUELS AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | disclosed |
| EP-0753496-A2 | Process for the catalytic selective hydrogenation of multiple unsaturated organic substances | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202464-A1 | Fragrance Compounds | OR10J3, OR51E2, TAS2R5 | CES1 2861/4885CES2 1364/4885TRPA1 99/4885 |
| US-20190276387-A1 | PRECURSOR COMPOUNDS FOR FRAGRANT ALDEHYDES | HAAO, B3GNT2, NAA40 | CES1 708/4885CES2 597/4885TRPA1 1001/4885 |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | TRPA1, CYP1A1, TRPV1 | CES1 1265/4885CES2 96/4885TRPA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.