SCHEMBL3916202

SCHEMBL3916202

CC(Cc1ccccc1)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
CYP2D6 P10635 2/20 0.42
LMNA P02545 1/20 0.42
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
KCNH2 Q12809 1/20 0.39
EPHX2 P34913 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
TRPA1 O75762 1/20 0.38
CTSS P25774 1/20 0.38
SLC18A3 Q16572 2/20 0.37
CYP19A1 P11511 1/20 0.37
POLB P06746 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815734 0.81 SLC6A2 (0.42) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL27518415 0.81 ESR1 (0.52) SLC6A2LMNAHSD17B10CHRM2CHRM1
SCHEMBL9390741 0.81 SLC6A2 (0.55) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL25971519 0.79 SLC6A2 (0.44) SLC6A2TAAR1CYP2D6LMNACHRM2
SCHEMBL31106365 0.78 ALDH1A1 (0.44) SLC6A2TAAR1CYP2D6USP2HPGD
SCHEMBL18886609 0.77 SLC6A2 (0.45) SLC6A2TAAR1CYP2D6CHRM2CHRM1
SCHEMBL9834053 0.76 CYP2B6 (0.45) SLC6A2TAAR1CYP2D6LMNACHRM2
SCHEMBL4287108 0.75 EPHX2 (0.42) SLC6A2TAAR1CYP2D6HPGDCHRM2
SCHEMBL27637612 0.74 KEAP1 (0.46) CYP2D6LMNACHRM2CHRM1KCNH2
SCHEMBL9345869 0.74 SIGMAR1 (0.40) SLC6A2TAAR1CYP2D6LMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027174-A1 BRANCHED POLYOLS HAVING A STATISTICAL AVERAGE OF TWO OR MORE HYDROXYL GROUPS IN THE MOLECULE, PROCESS FOR THEIR PREPARATION AND USE THEREOF BASF Coatings AG (DE) 2009-02-25 EP claimed
WO-2007131674-A1 BRANCHED POLYOLS HAVING A STATISTICAL AVERAGE OF TWO OR MORE HYDROXYL GROUPS IN THE MOLECULE, PROCESS FOR THEIR PREPARATION AND USE THEREOF BASF COATINGS AG (DE) 2007-11-22 WO claimed
EP-2027174-A1 BRANCHED POLYOLS HAVING A STATISTICAL AVERAGE OF TWO OR MORE HYDROXYL GROUPS IN THE MOLECULE, PROCESS FOR THEIR PREPARATION AND USE THEREOF BASF Coatings AG (DE) 2009-02-25 EP disclosed
WO-2007131674-A1 BRANCHED POLYOLS HAVING A STATISTICAL AVERAGE OF TWO OR MORE HYDROXYL GROUPS IN THE MOLECULE, PROCESS FOR THEIR PREPARATION AND USE THEREOF BASF COATINGS AG (DE) 2007-11-22 WO disclosed