Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 8/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916695 | 1.00 | KMT2A (0.34) | KMT2ARORCCYP2C9POLBREN | |
| SCHEMBL1038040 | 0.94 | KMT2A (0.36) | KMT2ARORCCYP2C9POLBREN | |
| SCHEMBL1037800 | 0.91 | PKM (0.39) | KMT2ACYP2C9POLBRENALDH1A1 | |
| SCHEMBL1036350 | 0.90 | KMT2A (0.37) | KMT2ARORCCYP2C9POLBREN | |
| SCHEMBL3908950 | 0.90 | RORC (0.32) | KMT2ARORCPOLBREN | |
| SCHEMBL2683450 | 0.88 | LMNA (0.38) | KMT2ARORCCYP2C9POLBREN | |
| SCHEMBL3905612 | 0.86 | POLB (0.38) | KMT2ARORCCYP2C9POLBREN | |
| SCHEMBL3902379 | 0.85 | RORC (0.32) | RORCREN | |
| SCHEMBL3907620 | 0.85 | PKM (0.39) | KMT2ACYP2C9POLBRENALDH1A1 | |
| SCHEMBL3905192 | 0.84 | PKM (0.39) | KMT2ACYP2C9POLBRENALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |