SCHEMBL3917622

SCHEMBL3917622

[SiH3]C(CCCBr)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.35
TDP1 Q9NUW8 1/20 0.31
LTA4H P09960 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923259 0.81 KCNA3 (0.40) KCNA3LTA4HTSHR
SCHEMBL3815410 0.81 KIF11 (0.47) LTA4H
SCHEMBL3924731 0.79 TSHR (0.36) KCNA3TDP1LTA4HTSHR
SCHEMBL3924740 0.71 LTA4H (0.36) KCNA3LTA4HTSHR
SCHEMBL3923789 0.70 PPARA (0.34) KCNA3TSHR
SCHEMBL5031082 0.69 KCNA3 (0.44) KCNA3TDP1LTA4H
SCHEMBL18585417 0.67 LTA4H (0.36) KCNA3LTA4HTSHR
SCHEMBL188025 0.67 LTA4H (0.45) KCNA3TDP1LTA4HTSHR
SCHEMBL3950956 0.66 KCNA3 (0.71) KCNA3LTA4H
SCHEMBL6047033 0.66 TSHR (0.39) KCNA3TDP1LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed