SCHEMBL3917951

SCHEMBL3917951

CCO[Si](C)(OCC)OC(=O)CC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
NAAA Q02083 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431579 0.85 ALDH1A1 (0.39) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28049534 0.82 CYP1A2 (0.33) MGAMGAASIMGAM2
SCHEMBL3912037 0.82 ALDH1A1 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL28101995 0.80 CYP1A2 (0.32) MGAMGAASIMGAM2
SCHEMBL28415420 0.79 NAAA (0.31) NAAA
SCHEMBL3919518 0.78 MGAM (0.40) ALDH1A1MGAMGAASIMGAM2
SCHEMBL838934 0.78 ALDH1A1 (0.42) ALDH1A1
SCHEMBL7892098 0.78 ALDH1A1 (0.35) ALDH1A1MGAMGAASIMGAM2
SCHEMBL3912259 0.78 ALDH1A1 (0.35) ALDH1A1MGAMGAASIMGAM2
SCHEMBL10777423 0.78 ALDH1A1 (0.35) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed