SCHEMBL431579

SCHEMBL431579

CCC(=O)O[Si](C)(OC(=O)CC)OC(=O)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
NAAA Q02083 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
FFAR3 O14843 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
HIF1A Q16665 2/20 0.32
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
ESR1 P03372 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919518 0.87 MGAM (0.40) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL3917951 0.85 ALDH1A1 (0.33) ALDH1A1NAAAMGAMGAASI
SCHEMBL1291088 0.82
SCHEMBL7885704 0.82 ALDH1A1 (0.39) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL30825208 0.80 ALDH1A1 (0.38) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL741428 0.80 ALDH1A1 (0.38) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL29834082 0.80 ALDH1A1 (0.38) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL430933 0.79 ALDH1A1 (0.41) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL23322459 0.78
SCHEMBL30112934 0.78 ALDH1A1 (0.55) ALDH1A1FFAR3MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1530961-B1 Emulsion containing hollow organosilicon particles OREAL (FR) 2009-08-05 EP claimed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP claimed
EP-0274428-B1 ORGANOALKOXYSILANE-CONTAINING COATING COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-03-18 EP claimed
US-4904721-A PROTECTIVE COATINGS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-02-27 US claimed
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
WO-2016116488-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST ONE HYDROCARBON-BASED RESIN, AT LEAST A FIRST OILY PHASE AND AT LEAST A SECOND OILY PHASE L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116475-A1 O/O EMULSION CONTAINING MICROPARTICLES WITH A BREAK IN THE CURVATURED PART, COMPOSITIONS COMPRISING SAME AND USE OF MICROPARTICLES FOR STABILIZING THE O/O EMULSIONS L'OREAL (FR) 2016-07-28 WO disclosed
WO-2016116492-A1 OIL/OIL EMULSION COMPRISING SOLID MICROPARTICLES, AT LEAST A FIRST OILY PHASE, AT LEAST A SECOND OILY PHASE AND AT LEAST A THIRD OILY PHASE THAT ARE MUTUALLY IMMISCIBLE L'OREAL (FR) 2016-07-28 WO disclosed
US-20160158118-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2016-06-09 US disclosed
EP-3021948-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS L'OREAL (FR) 2016-05-25 EP disclosed
CN-104955523-A Method for reducing the appearance of skin pores and for making skin matte and aqueous composition for skin care comprising spindle-shaped particles OREAL 2015-09-30 CN disclosed
EP-0509213-B1 Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides HUELS CHEMISCHE WERKE AG (DE) 1996-04-10 EP disclosed
US-5187291-A Reacting monocarboxylic anhydrides with organochlorosilanes in presence of organic bases, then vacuum distillation HULS AKTIENGESELLSCHAFT (DE) 1993-02-16 US disclosed
EP-0509213-A1 Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides HÜLS AKTIENGESELLSCHAFT (DE) 1992-10-21 EP disclosed
EP-0274428-B1 ORGANOALKOXYSILANE-CONTAINING COATING COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-03-18 EP disclosed
US-4904721-A PROTECTIVE COATINGS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-02-27 US disclosed
EP-0274428-A2 Organoalkoxysilane-containing coating composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-07-13 EP disclosed
EP-0240952-A2 A method for producing a flaky material SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed
US-4349603-A THERMOPLASTIC RESIN HAVING A PRIMER COATING OF UNSATURATED SILANEDI-OR TRIOL/GRAFTED SYNTHETIC RUBBER AND AN EXTERIOR COATING OF A CR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160158118-A1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS NONO, SQLE, PFN1 ALDH1A1 3851/4885NAAA 4564/4885TDP1 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.