Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28704162 | 0.88 | PTGDR2 (0.42) | TSHRMEN1KMT2APTGDR2MCOLN3 | |
| SCHEMBL28467370 | 0.86 | TSHR (0.34) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL29504740 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRPTGDR2PDE10A | |
| SCHEMBL16166457 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRPTGDR2PDE10A | |
| SCHEMBL29282409 | 0.83 | PTGDR2 (0.36) | TSHRMEN1KMT2APTGDR2MCOLN3 | |
| SCHEMBL5985763 | 0.82 | PDE10A (0.34) | TSHRMEN1KMT2APTGDR2PDE10A | |
| SCHEMBL14157277 | 0.80 | TSHR (0.36) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL28513653 | 0.80 | SYK (0.51) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL14892331 | 0.80 | HTR6 (0.39) | — | |
| SCHEMBL1121066 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038266-A2 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Abbott Laboratories (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007140385-A2 | THIAZOLE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2007-12-06 | — | — | WO | disclosed |