Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29504740 | 1.00 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNASYKEPHX2 | |
| SCHEMBL17476551 | 0.92 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1LMNASYKEPHX2 | |
| SCHEMBL8445070 | 0.90 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1EPHX2SMN1; SMN2MAPK1 | |
| SCHEMBL6086222 | 0.87 | PTGDR2 (0.42) | L3MBTL1EPHX2SMN1; SMN2MAPK1TSHR | |
| SCHEMBL17316352 | 0.85 | MCOLN3 (0.35) | ALDH1A1L3MBTL1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL3918082 | 0.85 | ALDH1A1 (0.38) | ALDH1A1LMNASYKEPHX2CFTR | |
| SCHEMBL19615032 | 0.84 | TSHR (0.43) | L3MBTL1LMNASMN1; SMN2MAPK1TSHR | |
| SCHEMBL14157165 | 0.84 | SMN1; SMN2 (0.34) | ALDH1A1L3MBTL1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL16684745 | 0.83 | PTGDR2 (0.36) | L3MBTL1EPHX2SMN1; SMN2MAPK1TSHR | |
| SCHEMBL1121066 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNASYKEPHX2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515579-A | Pyrrolo [2,3-b ] pyridine-3-carboxamide compositions and methods for ameliorating hearing loss | 洛克菲勒大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-111094267-B | Sulfonyl-substituted bicyclic compounds as ROR gamma inhibitors | 正大天晴药业集团股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114555592-A | 2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110981876-B | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-111094267-A | Sulfonyl-substituted bicyclic compounds as ROR gamma inhibitors | 正大天晴药业集团股份有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-110981876-A | 8-substituted styrylxanthine derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-10 | — | — | CN | disclosed |
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |
| WO-2014167530-A1 | CANNABINOID COMPOUNDS | BOWDEN MATTHEW JAMES (NZ) | 2014-10-16 | — | — | WO | disclosed |