SCHEMBL391840

SCHEMBL391840

[CH2]c1ccccc1C(C)CC

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TRPA1 O75762 1/20 0.37
ATM Q13315 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
RORC P51449 1/20 0.36
HTT P42858 2/20 0.36
HSP90AA1 P07900 2/20 0.33
HSP90AB1 P08238 2/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994607 0.83 TSHR (0.73) TSHRGABRA1GABRB2KDM4EL3MBTL1
SCHEMBL820441 0.83 TSHR (0.41) TSHRGABRA1GABRB2TRPA1
SCHEMBL816635 0.79 TSHR (0.38) TSHRKDM4E
SCHEMBL814926 0.79 TSHR (0.40) TSHRGABRA1GABRB2TRPA1
Hydrogen Peroxide SCHEMBL3675725 0.78 TSHR (0.74) TSHRGABRA1GABRB2KDM4EL3MBTL1
SCHEMBL815937 0.78 TSHR (0.37) TSHR
SCHEMBL2118347 0.78 TSHR (0.37) TSHRKDM4EL3MBTL1
SCHEMBL2118316 0.77 TSHR (0.35) TSHRGABRA1GABRB2KDM4EL3MBTL1
SCHEMBL9746544 0.77 CSNK1E (0.37) TSHR
SCHEMBL944816 0.76 TSHR (0.64) TSHRGABRA1GABRB2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230072538-A1 METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE AND PATTERN FORMATION METHOD TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-03-09 US claimed
CN-102584829-A Pyrazole and pyrazine diketone derivative and application thereof UNIV SHANDONG 2012-07-18 CN claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
CN-101367819-B 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG 2010-08-18 CN claimed
EP-1845786-B1 FORMULATIONS CONTAINING MICROENCAPSULATED ESSENTIAL OILS BOTANOCAP LTD (IL) 2010-03-10 EP claimed
CN-101633675-A Preparation and application of 5-substituent group-6-substituent phenyl-2-ferrocenyl pyrazolo [1, 5-a] pyrazine-4(5H)-ketone derivative UNIV SHANDONG 2010-01-27 CN claimed
CN-101367819-A 5-substituent-2-(4-substituted phenyl)-6,7-dihydrogen pyrazole-[1,5-a]pyrazine-4(5H)-ketone derivant and uses thereof UNIV SHANDONG (CN) 2009-02-18 CN claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
EP-3904360-B1 NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2024-07-03 EP disclosed
CN-113677686-B Novel tetraarylborate compounds, catalyst compositions comprising the same, and process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins by using the same 沙特基础工业爱思开NEXLENE私人有限公司 2024-06-11 CN disclosed
US-11718758-B2 Aqueous dispersion of colored particles MITSUBISHI PENCIL COMPANY, LIMITED (JP) 2023-08-08 US disclosed
EP-3725854-B1 COLORED PARTICLE AQUEOUS DISPERSION MITSUBISHI PENCIL CO (JP) 2023-07-05 EP disclosed
WO-1994012033-A1 USE OF TRIAZOLYLALKYLDIOXOLANE DERIVATIVES AS MICROBICIDES TO PROTECT MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1994-06-09 WO disclosed
EP-0342710-B1 MACROLIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-05-19 EP disclosed
EP-0249015-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
EP-0342710-A1 Macrolide compounds, their preparation and their use Sankyo Company Limited (JP) 1989-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TSHR 4680/4885GABRA1 3688/4885GABRB2 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.