Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816635 | 0.88 | TSHR (0.38) | TSHRSMN1; SMN2POLBCYSLTR2CYSLTR1 | |
| SCHEMBL815937 | 0.86 | TSHR (0.37) | TSHRCYSLTR2CYSLTR1 | |
| SCHEMBL9746544 | 0.85 | CSNK1E (0.37) | TSHRGPR84CYSLTR2CYSLTR1 | |
| SCHEMBL31380293 | 0.84 | TSHR (0.48) | TSHRSMN1; SMN2FFAR1GPR84POLB | |
| SCHEMBL391840 | 0.83 | TSHR (0.59) | TSHRTRPA1GABRA1GABRB2 | |
| SCHEMBL817442 | 0.81 | FFAR1 (0.34) | TSHRSMN1; SMN2FFAR1GPR84AOC3 | |
| SCHEMBL14864537 | 0.78 | TSHR (0.43) | TSHRSMN1; SMN2FFAR1GPR84POLB | |
| SCHEMBL815082 | 0.78 | TSHR (0.35) | TSHRFFAR1GPR84AOC3 | |
| SCHEMBL2697157 | 0.77 | TSHR (0.42) | TSHRSMN1; SMN2FFAR1GPR84POLB | |
| SCHEMBL11800593 | 0.77 | ESR1 (0.45) | TSHRSMN1; SMN2FFAR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | claimed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-08-09 | — | — | US | disclosed |
| US-8173828-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110288249-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-11-24 | — | — | US | disclosed |
| US-7868197-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-4822506-A | Lubricant additives containing sulfur | CIBA-GEIGY CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0271437-A1 | Sulphurized lubricant additives | CIBA-GEIGY AG (CH) | 1988-06-15 | — | — | EP | disclosed |
| EP-0031792-B1 | POLYESTER COMPOSITIONS HAVING A REDUCED CORROSIVE EFFECT ON METALS, AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-07-31 | — | — | EP | disclosed |
| US-4373044-A | REDUCING CORROSIVE ACTION ON METALS OR ALLOYS BY INCLUDING AEROSOL OF AN OXIDE | CIBA-GEIGY CORPORATION (US) | 1983-02-08 | — | — | US | disclosed |
| EP-0031792-A2 | Polyester compositions having a reduced corrosive effect on metals, and their use | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |
| EP-0016722-A1 | Stabilised flame-resistant plastics moulding composition and process for stabilising plastics made flame-resistant with organic bromine compounds | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | disclosed |
| US-3988378-A | ANTISTATIC AGENTS, STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3936422-A | Anti-static modified thermoplastics | CIBA-GEIGY CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | TSHR 4680/4885SMN1; SMN2 3076/4885FFAR1 2521/4885 |
| US-20110288249-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | OPRM1, POLM, AP1M1 | TSHR 1993/4885SMN1; SMN2 4192/4885FFAR1 3091/4885 |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | OPRM1, POLM, AP1M1 | TSHR 1993/4885SMN1; SMN2 4192/4885FFAR1 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.