Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586781 | 0.95 | LMNA (0.50) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL6231293 | 0.89 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1ADRA1ASCN1A | |
| SCHEMBL28429232 | 0.87 | ALDH1A1 (0.57) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL12083363 | 0.86 | LMNA (0.55) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL7894937 | 0.84 | HPGD (0.55) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL9450061 | 0.84 | LMNA (0.56) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL10789528 | 0.84 | ALDH1A1 (0.66) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL30010658 | 0.84 | ALDH1A1 (0.66) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL12083362 | 0.83 | ALDH1A1 (0.62) | LMNATSHRTDP1ALDH1A1HPGD | |
| SCHEMBL31438950 | 0.83 | ALDH1A1 (0.72) | LMNATSHRTDP1ALDH1A1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039279-B2 | Aromatic esters for controlling agricultural spray drift | DOW AGROSCIENCES LLC (US) | 2018-08-07 | — | — | US | claimed |
| CN-112516084-A | In situ gel containing cyclosporine micelles as sustained release ophthalmic drug delivery system | 艾威药业(珠海)有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-107466292-B | Novel 1, 4-bis (3-aminopropyl) piperazine derivatives and use thereof | 国家医疗保健研究所 | 2020-05-01 | — | — | CN | disclosed |
| EP-2833715-B9 | AROMATIC ESTERS FOR CONTROLLING AGRICULTURAL SPRAY DRIFT | DOW AGROSCIENCES LLC (US) | 2019-07-17 | — | — | EP | disclosed |
| US-10039279-B2 | Aromatic esters for controlling agricultural spray drift | DOW AGROSCIENCES LLC (US) | 2018-08-07 | — | — | US | disclosed |
| CN-107466292-A | Novel 1, 4-bis (3-aminopropyl) piperazine derivatives and use thereof | 国家医疗保健研究所 | 2017-12-12 | — | — | CN | disclosed |
| CN-106233141-A | Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell | 罗伯特·I·汉金 | 2016-12-14 | — | — | CN | disclosed |
| CN-102105125-B | Absorbent products with wetness sensors | KIMBERLY CLARK CO | 2015-02-25 | — | — | CN | disclosed |
| EP-2833715-A2 | AROMATIC ESTERS FOR CONTROLLING AGRICULTURAL SPRAY DRIFT | Dow AgroSciences LLC (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2014007887-A2 | AROMATIC ESTERS FOR CONTROLLING AGRICULTURAL SPRAY DRIFT | DOW AGROSCIENCES LLC (US) | 2014-01-09 | — | — | WO | disclosed |
| CN-1602201-A | Peptides and related compounds having thrombopoietic activity | AMGEN INC (US) | 2005-03-30 | — | — | CN | disclosed |
| EP-0988044-A4 | CENTIPEDA PLANT EXTRACT | AMELIO FRANK D (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020044977-A1 | CENTIPEDA PLANT EXTRACT | D'AMELIO, FRANK | 2002-04-18 | — | — | US | disclosed |
| US-6071959-A | FOR RELIEVING PAIN OF LOWER GASTROINTESTINAL TRACT BY RECTAL OR ORAL ADMINISTRATION OF A COMPLEX OF AMIDE-TYPE LOCAL ANAESTHETIC AND POLYACRYLATE WITH CARRIER, DILUENT AND/OR EXCIPIENT | RHODES JOHN (GB) | 2000-06-06 | — | — | US | disclosed |
| EP-0988044-A1 | CENTIPEDA PLANT EXTRACT | d'Amelio, Frank (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0914106-A1 | PHARMACEUTICAL PRODUCTS CONTAINING A COMPLEX OF AN AMIDE-TYPE LOCAL ANESTHETIC AND A POLYACRYLATE | RHODES, John (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5843482-A | Products and processes for the treatment of the alimentary canal | TILLOTTS PHARMA AG (CH) | 1998-12-01 | — | — | US | disclosed |
| WO-1998032454-A1 | CENTIPEDA PLANT EXTRACT | D'AMELIO, FRANK (US) | 1998-07-30 | — | — | WO | disclosed |
| WO-1997044021-A1 | PHARMACEUTICAL PRODUCTS CONTAINING A COMPLEX OF AN AMIDE-TYPE LOCAL ANESTHETIC AND A POLYACRYLATE | RHODES JOHN (GB) | 1997-11-27 | — | — | WO | disclosed |
| EP-0540613-B1 | PRODUCTS AND PROCESSES FOR THE TREATMENT OF THE ALIMENTARY CANAL | SLAGEL DAVID (CH) | 1996-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039279-B2 | Aromatic esters for controlling agricultural spray drift | DDT, AHR, SLC43A1 | LMNA 4708/4885TSHR 650/4885TDP1 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.