⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16134038 | 1.00 | — | — | |
| SCHEMBL18294833 | 1.00 | — | — | |
| SCHEMBL5983404 | 0.83 | — | — | |
| SCHEMBL540360 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL22793359 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL2338941 | 0.79 | CHRNB2 (0.40) | — | |
| SCHEMBL6657579 | 0.78 | CHRNB2 (0.66) | — | |
| SCHEMBL160033 | 0.77 | — | — | |
| SCHEMBL6721825 | 0.77 | — | — | |
| SCHEMBL12973059 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | VORONOI INC. (KR) | 2024-07-25 | — | — | US | claimed |
| US-8349982-B2 | Macromonomers and hydrogels | WILLIAM MARSH RICE UNIVERSITY (US) | 2013-01-08 | — | — | US | claimed |
| US-20090111928-A1 | Novel Macromonomers and Hydrogels | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-30 | — | — | US | claimed |
| WO-2007127785-A2 | NOVEL INJECTABLE MACROMONOMERS FOR THE FABRICATION OF HYDROGELS | WILLIAM MARSH RICE UNIVERSITY (US) | 2007-11-08 | — | — | WO | claimed |
| US-20160257686-A1 | Purinone Derivatives as Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2016-09-08 | — | — | US | disclosed |
| US-20140142099-A1 | Purinone Derivatives as Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8367777-B2 | Blocks having different glass transition temperatures, at least one of which having a glass transition temperature of less than or equal to 20 degrees C. | L'OREAL (FR) | 2013-02-05 | — | — | US | disclosed |
| US-8349982-B2 | Macromonomers and hydrogels | WILLIAM MARSH RICE UNIVERSITY (US) | 2013-01-08 | — | — | US | disclosed |
| US-20090111928-A1 | Novel Macromonomers and Hydrogels | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-04-30 | — | — | US | disclosed |
| WO-2007127785-A2 | NOVEL INJECTABLE MACROMONOMERS FOR THE FABRICATION OF HYDROGELS | WILLIAM MARSH RICE UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20030124074-A1 | Adhesive block ethylenic copolymers, cosmetic compositions containing them and cosmetic use of these copolymers | L'OREAL (FR) | 2003-07-03 | — | — | US | disclosed |