Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617786 | 0.83 | ALDH1A1 (0.50) | GSK3BALDH1A1MAPK1HIF1ATRPA1 | |
| SCHEMBL27596818 | 0.80 | F2R (0.46) | ALDH1A1HTTMAPTKMT2AHPGD | |
| SCHEMBL6420545 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KMT2AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL8495468 | 0.76 | PRNP (0.50) | ALDH1A1MAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11737575 | 0.75 | ALDH1A1 (0.61) | GSK3BALDH1A1MAPK1HIF1ATRPA1 | |
| SCHEMBL588389 | 0.74 | PRNP (0.53) | ALDH1A1LMNAMAPTKMT2AHPGD | |
| SCHEMBL29532264 | 0.73 | ALDH1A1 (0.41) | GSK3BALDH1A1MAPK1HIF1ATRPA1 | |
| SCHEMBL17982450 | 0.73 | ALDH1A1 (0.41) | GSK3BALDH1A1MAPK1HIF1ATRPA1 | |
| SCHEMBL28482995 | 0.72 | PRNP (0.39) | ALDH1A1KMT2AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL1873518 | 0.72 | KMT2A (0.41) | ALDH1A1LMNAKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907360-A4 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | GLADE ORGANICS PRIVATE LTD (IN) | 2009-04-01 | — | — | EP | disclosed |
| EP-1907360-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | Glade Organics Private Limited (IN) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007003982-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | GLADE ORGANICS PRIVATE LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |