Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728428 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15PRNPMEN1KMT2A | |
| SCHEMBL8495468 | 0.81 | PRNP (0.50) | ALDH1A1ALOX15PRNPMEN1KMT2A | |
| SCHEMBL123057 | 0.81 | ALDH1A1 (0.54) | ALDH1A1ALOX15MEN1KMT2ANPC1 | |
| SCHEMBL4921450 | 0.80 | ALDH1A1 (0.46) | ALDH1A1ALOX15PRNPMEN1KMT2A | |
| SCHEMBL28789921 | 0.80 | ALDH1A1 (0.43) | ALDH1A1ALOX15PRNPMEN1KMT2A | |
| SCHEMBL7596116 | 0.80 | ALDH1A1 (0.52) | ALDH1A1ALOX15TSHRHPGDCES2 | |
| SCHEMBL1552127 | 0.80 | ALDH1A1 (0.43) | ALDH1A1ALOX15PRNPMEN1KMT2A | |
| SCHEMBL11815709 | 0.79 | ALDH1A1 (0.37) | ALDH1A1ALOX15 | |
| SCHEMBL588389 | 0.79 | PRNP (0.53) | ALDH1A1ALOX15PRNPKMT2ASMN1; SMN2 | |
| SCHEMBL17938254 | 0.78 | ALDH1A1 (0.63) | ALDH1A1ALOX15MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731626-A1 | PI3K INHIBITORS AND USE THEREOF | Regor Pharmaceuticals, Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12281060-B2 | Remodilins for airway remodeling and organ fibrosis | THE UNIVERSITY OF CHICAGO (US) | 2025-04-22 | — | — | US | disclosed |
| WO-2024260464-A1 | PI3K INHIBITORS AND USE THEREOF | REGOR PHARMACEUTICALS, INC. (US) | 2024-12-26 | — | — | WO | disclosed |
| US-20240415851-A1 | REMODILINS TO PREVENT OR TREAT CANCER METASTASIS, GLAUCOMA, AND HYPOXIA | THE UNIVERSITY OF CHICAGO (US) | 2024-12-19 | — | — | US | disclosed |
| US-20220177422-A1 | REMODILINS FOR AIRWAY REMODELING AND ORGAN FIBROSIS | THE UNIVERSITY OF CHICAGO (US) | 2022-06-09 | — | — | US | disclosed |
| US-20220040207-A1 | REMODILINS TO PREVENT OR TREAT CANCER METASTASIS, GLAUCOMA, AND HYPOXIA | THE UNIVERSITY OF CHICAGO (US) | 2022-02-10 | — | — | US | disclosed |
| EP-3946301-A1 | REMODILINS FOR AIRWAY REMODELING AND ORGAN FIBROSIS | The University of Chicago (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020206118-A1 | REMODILINS TO PREVENT OR TREAT CANCER METASTASIS, GLAUCOMA, AND HYPOXIA | THE UNIVERSITY OF CHICAGO (US) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020206109-A1 | REMODILINS FOR AIRWAY REMODELING AND ORGAN FIBROSIS | THE UNIVERSITY OF CHICAGO (US) | 2020-10-08 | — | — | WO | disclosed |
| EP-1554360-A2 | ORGANIC ELECTROLUMINESCENT COMPOSITIONS | 3M Innovative Properties Company (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004099338-A2 | ORGANIC ELECTROLUMINESCENT COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-11-18 | — | — | WO | disclosed |
| EP-1237839-A2 | PROCESS FOR PRODUCING 3-BROMOBENZOYL HALIDES | ALBEMARLE CORPORATION (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2002057281-A2 | AMINOGLYCOSIDES AS ANTIBIOTICS | WAYNE STATE UNIVERSITY (US) | 2002-07-25 | — | — | WO | disclosed |
| US-6271417-B1 | Process for producing 3-bromobenzoyl halides | ALBEMARBLE CORPORATION | 2001-08-07 | — | — | US | disclosed |
| EP-1095005-A1 | PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES | ALBEMARLE CORPORATION (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2001021565-A2 | PROCESS FOR PRODUCING 3-BROMOBENZOYL HALIDES | ALBEMARLE CORPORATION (US) | 2001-03-29 | — | — | WO | disclosed |
| US-6096920-A | LARGE-SCALE PRODUCTION OF CERTAIN AROMATICALLY-SUBSTITUTED ALIPHATIC CARBOXYLIC ACIDS AND THEIR ACID DERIVATIVES | ALBEMARLE CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |
| WO-2000002840-A1 | PREPARATION OF CARBOXYLIC COMPOUNDS AND THEIR DERIVATIVES | ALBEMARLE CORPORATION (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0332988-A2 | 2-Aryl-benzoxazoles and 2'-hydroxybenzanilides | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220040207-A1 | REMODILINS TO PREVENT OR TREAT CANCER METASTASIS, GLAUCOMA, AND HYPOXIA | HIF1AN, RHOXF2, HIF1A | ALDH1A1 2857/4885ALOX15 3924/4885PRNP 4574/4885 |
| US-20220177422-A1 | REMODILINS FOR AIRWAY REMODELING AND ORGAN FIBROSIS | MYLK, MFAP1, FIBP | ALDH1A1 3220/4885ALOX15 3082/4885PRNP 4330/4885 |
| US-12281060-B2 | Remodilins for airway remodeling and organ fibrosis | MYLK, MFAP1, FIBP | ALDH1A1 3220/4885ALOX15 3082/4885PRNP 4330/4885 |
| US-20240415851-A1 | REMODILINS TO PREVENT OR TREAT CANCER METASTASIS, GLAUCOMA, AND HYPOXIA | HIF1AN, RHOXF2, HIF1A | ALDH1A1 2857/4885ALOX15 3924/4885PRNP 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.