Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919033 | 0.86 | MEN1 (0.54) | SIGMAR1SLC22A2HTR3ESLC22A1SLC22A3 | |
| SCHEMBL17329339 | 0.82 | SLC22A2 (0.46) | SIGMAR1SLC22A2HTR3ESLC22A1SLC22A3 | |
| SCHEMBL17329388 | 0.80 | SLC22A2 (0.43) | SIGMAR1SLC22A2HTR3ESLC22A1SLC22A3 | |
| SCHEMBL17360623 | 0.79 | SLC22A2 (0.50) | SIGMAR1SLC22A2HTR3ESLC22A1SLC22A3 | |
| SCHEMBL3919505 | 0.79 | TP53 (0.42) | SIGMAR1SLC22A2HTR3ESLC22A1SLC22A3 | |
| SCHEMBL16935719 | 0.77 | TP53 (0.50) | MEN1KMT2ATP53ALDH1A1GLA | |
| SCHEMBL6920739 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2ATP53ALDH1A1GLA | |
| SCHEMBL10824119 | 0.75 | MEN1 (0.53) | MEN1KMT2ATP53ALDH1A1GLA | |
| SCHEMBL6261729 | 0.75 | TP53 (0.58) | MEN1KMT2ATP53ALDH1A1GLA | |
| SCHEMBL3911915 | 0.75 | KMT2A (0.48) | SIGMAR1MEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |